Inducer (genetics)
In genetics, an inductor is a molecule that increases the transcription of regulated genes. The inducer binds to a repressor protein , which then detaches from its binding site on the DNA, the operator . This allows the RNA polymerase to bind to the promoter and initiate transcription. The genetic concept of the inducer was discussed extensively by Jacob and Monod in 1961.
Examples
- The induction of the lactose operon ( lac operon) by the inducer allolactose (a metabolic product of lactose ).
- The induction of the tet -operon by the antibiotic tetracycline .
Individual evidence
- ↑ F. Jacob & J. Monod (1961): Genetic regulatory mechanisms in the synthesis of proteins. In: J. Mol. Biol. Vol. 3, pp. 318-356. PMID 13718526
literature
- Robert C. King, William D. Stansfield, Pamela K. Mulligan: A Dictionary of Genetics. 7th edition. Oxford University Press, Oxford et al. 2006, ISBN 0-19-530762-3 .
Web links
Wiktionary: Inductor - explanations of meanings, word origins, synonyms, translations
