Ion Gresser

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Ion Gresser (* 1928 ) is an American immunologist working in France, known for research on interferons .

Gresser (son of the New York lawyer William Gresser) carried out research in the 1960s at the Institute de Recherche Scientifique sur le Cancer ( Institut Gustave Roussy ) in Villejuif . His preoccupation with interferon had already begun in the USA when he was a post-doctoral student in the laboratory of John Franklin Enders in Boston. He found interferon in patients with flu and diseases of the central nervous system.

In the late 1960s, he sparked research interest in interferon by showing that it slowed the growth of tumors in mice and stimulated lymphocytes that attacked the tumors.

In 1961 he showed that leukocytes infected with Sendai virus produced large amounts of interferon. The Finnish virologist Kari Cantell perfected this into a process that made it possible for the first time to obtain larger amounts of interferon.

In the 2000s he was part of an INSERM research group at the Center des Recherches Biomedicales des Cordeliers in Paris.

In 1983 he received the Avery Landsteiner Prize .

Individual evidence

  1. for example Gresser, Chantal Bourali Exogenous Interferon and Inducers of Interferon in the Treatment of Balb / c Mice inoculated with RC19 Tumour Cells , Nature, Volume 223, 1969, p. 844, Gresser, Bourali, Levy, Fontaine-Brouty-Boyé, Thomas Increased survival in mice inoculated with tumor cells and treated with interferon preparations , Proc. Nat. Acad. Sci., Vol. 63, 1969, pp. 51-57 and the same in Compte Rendus Acad. Sci., Volume 268, 1969, p. 994, Gresser, Daniele Brouty-Boyé, Marie-Therese Thomas, Alvaro Macieira-Coelho Interferon and Cell Division I: Inhibition of the multiplication of mouse leukemia L 1210 cells in vitro by interferon preparations , Proc. Nat. Acad. Science USA, Volume 66, 1970, pp. 1052-1058, PMC 335785 (free full text), Gresser, Chantal Maury, Daniele Brouty-Boyé Mechanism of the antitumour effect of interferon in mice , Nature, Volume 239, 1972, p. 167 -168
  2. Ion Gresser Interferon: an unfolding tale , Journal of Interferon and Cytokine Research, Volume 27, 2007, pp. 447-452