Kinetosome
| Parent |
| MTOC |
| Gene Ontology |
|---|
| QuickGO |
Kinetosomes occur in cells that are covered with cilia (cilia). They are usually located in a row below the cell membrane at the base of cilia, which is why they are also called basal bodies and are structured like centrioles . In their entirety, they are referred to as the terminal web.
Cilia arise from the basal bodies that are still inside the cell and protrude as a long, thread-like structure over the cell membrane. The protruding part ((+) - end) is the ciliate. In the tubular shaft made up of nine pairs of microtubules (complete A and incomplete B tubules) there is an additional central microtubule pair in secondary cilia , so that the entire structure shows a characteristic pattern: 9x2 + 2 (9 times 2 plus 2; 9 × 2 outer and 2 inner microtubules). This structure of actively movable cilia can be found throughout the animal kingdom.
The task of the motile cilia of epithelial cells is to transport fluids or particles across the cell surface. The actual flicker that enables this function comes about through the movement of axonemal dynein , which displaces the A tubule of one microtubule doublet against the B tubule of the neighboring one. The result is a bending because the doublets are anchored together in the kinetosomes. Such cells of the ciliated epithelium occur in humans z. B. in the fallopian tube and in the bronchi .
literature
- Udo M. Spornitz: Anatomy and Physiology: Textbook and atlas for care and health professions. 4th, completely revised Edition. Springer Medicine, Heidelberg 2004, ISBN 3-540-20600-0 .
- R. Lüllmann-Rauch: pocket textbook histology. 3. Edition. Thieme, Stuttgart / New York 2009, ISBN 978-3-13-129243-8