Coronary flow reserve

from Wikipedia, the free encyclopedia

Physiologically , the coronary flow reserve (CFR of coronary flow reserve) is the quotient of the maximum blood - volume flow in the coronary arteries under load and blood volume flow in the coronary arteries at rest. It is therefore the maximum additional volume flow that the heart muscle can supply when it is stressed and has an increased need for blood supply.

It is usually given as the quotient of the maximum load and idle volume flow.

In healthy people, the CFR can be 6 or higher; Values ​​above 3.5 are considered normal. The CFR is decreased, among other things, in stenoses in the coronary arteries, in high blood pressure , in cardiac syndrome X and in hypertrophic cardiomyopathy .

The gold standard for determining the coronary flow reserve is the examination with an intracoronary Doppler wire as part of a cardiac catheter examination . In addition to PET and transthoracic echocardiography in the LAD used. What all methods have in common is that an examination is first carried out at rest and then repeated under drug exposure, usually with adenosine .

Individual evidence

  1. a b M. Zamir: The Physics of Coronary Blood Flow. 2005, ISBN 0-387-25297-5 , pp. 27ff.
  2. P. Petkow-Dimitrov: Coronary Flow Reserve: Measurement and Application: Focus on Transthoracic Doppler Echocardiography. 2002, ISBN 1-4020-7213-9 , p. 5.
  3. ^ A b P. Petkow-Dimitrov: Transthoracic Doppler Echocardiography: Noninvasive Diagnostic Window for Coronary Flow Assessment. Volume 5 (2), 2004, pp. 55-65.