MALT lymphoma
| Classification according to ICD-10 | |
|---|---|
| C88.4 | Extranodal marginal zone B-cell lymphoma of the mucosa-associated lymphatic tissue [MALT lymphoma] |
| ICD-10 online (WHO version 2019) | |
The MALT lymphoma or MALToma is a mucosal -assoziiertes non-Hodgkin's lymphoma .
PAINT
MALT is an acronym for M ucosa A ssociated L ymphoid T issue (or M ucous membrane A ssociated L ymphoid T issue , engl. For mucosal-associated lymphoid tissue). It is found in areas of the mucous membrane (including the conjunctiva ) that are the main entry points for antigens . Here are lymphocytes sensitized, which then in regional lymph nodes hike then stimulating to walk to their original ( "homing") or other mucosal areas, eventually carried a strong production of immunoglobulin IgA .
Localization of the MALT lymphomas
MALT lymphomas (predominantly B-cell lymphomas) usually occur in the stomach . But they can also occur in the lungs , thyroid gland , skin , salivary glands , the eye or elsewhere. A Musshoff staging of gastrointestinal lymphomas has been in use since 1975.
Special forms
The primary lymphomas of the stomach are divided into indolent and aggressive forms. The benign forms make up around 40% of gastric lymphomas and are almost exclusively MALT tumors, which can be caused by a long-term infection of the gastric mucosa with the pathogen Helicobacter pylori . An eradication of the pathogen may result in the early stages of the disease for curing the lymphoma.
Even the Mediterranean lymphoma is expected to MALT lymphoma.
swell
- ^ Possinger, Regierer, Engelhardt: Specialist in hematology. Elsevier.
- ^ SS Yoon et al .: The diminishing role of surgery in the treatment of gastric lymphoma. In: Ann Surg . 2004 Jul; 240 (1), pp. 28-37. PMID 15213615
- ↑ N. Ahmed, LA Sechi: Helicobacter pylori and gastroduodenal pathology: new threats of the old friend. In: Ann Clin Microbiol Antimicrob. 2005 Jan 5; 4, p. 1. PMID 15634357
