Melanosis oculi
| Classification according to ICD-10 | |
|---|---|
| D31. | Benign neoplasm of the eye and its appendages |
| ICD-10 online (WHO version 2019) | |
The melanosis oculi , more rarely (congenital) ocular melanosis called, is a congenital hyperpigmentation of the skin average eye ( uveal or lamina episcleralis ) extending in a striking Heterochromie represents. The iris can appear so dark that you can hardly see the pupil.
If skin pigmentation can also be observed in addition to the pigmentation of the eye, this is referred to as nevus ota . In the differential diagnosis, melanosis oculi must be differentiated from other, potentially more dangerous, acquired melanoses of the eye .
Pathology and epidemiology
The melanosis oculi is innate in most cases. The frequency is given as 38 per 100,000 for the white population and 14 per 100,000 for the dark-skinned population. Significantly higher values are estimated for Asians.
The cause of melanosis oculi is the unilateral increase in pigment-rich melanocytes .
From a melanosis oculi can a choroidal melanoma (malignant uveal melanoma) develop. The probability of such a degeneration is about 5%. The hormonal influence of pregnancy can further increase the probability. Regular eye checks are therefore recommended by most doctors.
therapy
The melanosis oculi cannot be removed surgically. Regular ophthalmological checks are recommended.
further reading
- NE Bechrakis et al: Ocular melanomas. In: Der Onkologe 12, 2006, pp. 213-221. doi : 10.1007 / s00761-006-1033-7
- J. Heine: Contribution to the acquired melanosis oculi. In: Klin Monatsbl Augenheilkd 195, 1989, pp. 379-381. doi : 10.1055 / s-2008-1050060
Individual evidence
- ↑ a b c B. Ehall and G. Langmann: Kongenitale ocular melanosis. In: Spektrum der Augenheilkunde 8, 1994, pp. 192-194. doi : 10.1007 / BF03163707
- ↑ B. Samuels: Melanosis oculi and sector-shaped melanosis with melanosarcoma of the choroid. ( Page no longer available , search in web archives ) Info: The link was automatically marked as defective. Please check the link according to the instructions and then remove this notice. In: Graefes Archiv der Ophthalmologie 154, 1953, pp. 361-367.
- ↑ a b G. Gudacker: The melanoma of the uvea: 10-year follow-up and clinical prognostic factors. Dissertation, Medical Faculty Charité - Universitätsmedizin Berlin, 2010
- ↑ H. Wüstemeyer include: tumors of the conjunctiva. ( Memento of the original from December 16, 2013 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. Retrieved July 4th
