Mesangium

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In anatomy, the mesangium is the connective tissue stalk made of extracellular matrix from which the glomerular capillary loops emerge. This connective tissue contains cells called mesangial cells or mesangiocytes . Because they are located inside the kidney corpuscle (intraglomerular), they are also known as intraglomerular mesangial cells . Mesangial cells are important for capillary function because they are contractile (can contract) and support the capillary walls and are capable of phagocytosis .

The intraglomerular mesangium cells are separated from the extraglomerular mesangium cells , which are located outside at the vascular pole of the renal corpuscle. The extra-glomerular mesangial cells are part of the juxtaglomerular apparatus . They are also known as Goormaghtigh cells after the Belgian pathologist Norbert Goormaghtigh .

Schematic structure of a kidney corpuscle:
Renal corpuscle.svg

      A kidney corpuscles
      B main piece
      C middle piece
      D juxtaglomerular apparatus

  1. Basement membrane
  2. Bowman's capsule, parietal leaf
  3. Bowman's capsule, visceral leaf
    a
    ) Podocyte feet b) Podocyte
  4. Bowman's capsule lumen (urinary space)
  5. a) Mesangium - the intraglomerular mesangium cells
    b) Mesangium - the extraglomerular mesangium cells
  6. Juxtaglomerular cells
  7. Macula densa
  8. Myocytes (muscle cells in the arteriolar wall)
  9. Arteriola afferens
  10. glomerular capillaries
  11. Arteriola efferens

swell

  • Renate Lüllmann-Rauch: Pocket textbook histology Georg Thieme Verlag, 2006, ISBN 3-13-129242-3 , p. 448.
  • Walther Graumann: CompactLehrbuch Anatomie 3 Schattauer Verlag, 2004, ISBN 3-7945-2063-7 , p. 234, p. 238.