Fahr's disease
| Classification according to ICD-10 | |
|---|---|
| G23.8 | Other specified degenerative diseases of the basal ganglia - calcification of the basal ganglia |
| ICD-10 online (WHO version 2019) | |
The drive's disease or Fahr's syndrome (also striatodentale calcification ) is a calcification of the basal ganglia of the brain that are not on atherosclerotic due processes. The disease was first described in 1931 by Theodor Fahr (1877–1945).
to form
Fahr's disease can occur idiopathically sporadically or as a family disease, both autosomal dominant and recessive inheritance. Fahr's disease can also occur symptomatically in the context of hypoparathyroidism and pseudohypoparathyroidism .
Symptoms
This basal ganglia calcification must be described as an incidental finding in those 40% of those affected who do not show any symptoms. The entitlement as an independent illness is therefore also partly doubted.
The symptomatic forms include headache , speech disorders , slowly progressing dementia and extrapyramidal symptoms . Correcting the calcium level can significantly improve the latter.
literature
- T. Fahr: Idiopathic calcification of the brain vessels. In: Central sheet for general pathology and pathological anatomy. 1930-1931, 50, pp. 129-133.
- H. Grehl, F. Reinhardt: Checklist neurology. 3. Edition. Georg Thieme Verlag, Stuttgart 2005, pp. 509-510.
