Nun-Marie Syndrome

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The Nun-Marie syndrome goes back to the neurologists Max Nonne (1861-1959) and Pierre Marie (1853-1940). It is a cerebellar heredo ataxia . Atrophies (tissue shrinkage) of the cerebral cortex are anatomical findings.

In the case of the dominant hereditary disease, symptoms usually show up from the age of 35. Cardinal symptoms are gait and speech disorders ("lion's voice"), spasticity, cranial nerve disorders and dementia.

Individual evidence

  1. ^ Poeck, Klaus: Neurology . 8th, revised and expanded edition. Berlin, Heidelberg, ISBN 978-3-662-08951-4 , pp. 464 ( google.de [accessed on September 18, 2019]).