Pierre Marie

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Pierre Marie

Pierre Marie (born September 9, 1853 in Paris, † April 13, 1940 in Pradet near Cannes ) was a French neurologist.

Life and education

Pierre Marie was born in Paris on September 9th . He came from an upper class family. At the end of his high school years, he only had to obey his father's wishes and study law in Paris . After three years he was finally able to enroll in the medical faculty. In 1878 he was appointed " Interne des Hôpitaux de Paris ". He was intern at Broca , Bouchard and Charcot at the Hôpital de la Salpêtrière . The doctoral dissertation ( 1883 ) was a "contribution to the research and recognition of the formes frustes of Graves' disease". In the following years ( 1886 ), together with his teacher Charcot, he published the work "On a special form of progressive muscular atrophy ...", a disease that was soon called the "Charcot-Marie amyotrophs", as well as an article about acromegaly .


In 1888 , Pierre Marie was appointed Médecin des Hôpitaux de Paris (head physician) at the Hôpital Salpêtrière , and in 1899 an associate professor at the Paris Medical Faculty. Then Marie became department director at Bicêtre Hospital, succeeding Dejerine . In 1907 Pierre Marie received the chair of pathological anatomy at the Paris Medical Faculty and returned to the Salpêtrière . After Dejerine's death in 1917 , he was given the chair of diseases of the nervous system . From 1918 he succeeded Charcot at the Hôpital Salpêtrière . In 1924 , Pierre Marie retired.

Pierre Marie left a work that has a prominent place in neurology . Pierre Marie had triggered lively reactions with his contributions to aphasia . Marie played the role of the third left frontal turn (so-called Broca region) for speech function. He put forward three pieces of evidence to support his thesis:

  • First: Damage to the Broca region is known without aphasia.
  • Second, there are cases of Broca's aphasia with an intact third forehead curl.
  • Thirdly, he showed in the case histories of Broca's initial cases that Broca's interpretations were influenced by the teachings of Franz Gall on phrenology .

The Foix-Chavany-Marie syndrome and the Marie-Foix-Alajouanine syndrome are named after him. Together with Wladimir Bechterew and Adolf von Strümpell , he described Bechterew's disease in 1898 .


  • Des formes frustes de la maladie de Basedow . Thèse de doctorat, Paris, 1883.
  • Sclerosis en plaques et maladies infectieuses. 1884.
  • Sur deux cas d ' acromégalie . 1886.
  • De la déviation faciale dans l'hémiplégie hystérique.
  • Sur une form particulière d'atrophie musculaire progressive; souvent familiale, débutant par les pieds et les jambes et atteignant tard les mains. Add. with Jean-Martin Charcot . Rev Méd, Paris, 1886, 6:97
  • Hystérie dans l'intoxication par le sulfure de carbone. 1888.
  • Ostéoarthropathie hypertrophiante pneumique. 1890.
  • Essays on Acromegaly. Add. with JD Souza-Leite. London, The New Sydenham Society 1891.
  • Leçons sur les maladies de la moëlle épinière. Paris, G. Masson 1892; German: Lectures on diseases of the spinal cord, Leipzig and Vienna, F. Deuticke 1894
  • Sur l'hérédo-ataxie cérébelleuse. Semaine médicale, Paris, 1893, 13: 444.
  • Leçons de clinique médicale. Hôtel-Dieu, 1894–1895.
  • Sur un syndrome clinique et urologique se montrant dans le diabète lévulosurique et caractérisé par un état mélancolique avec insomnie et impuissance. Add. with Robinson. 1897.
  • L'évolution du langage considéré au point de vue de l'étude de l'Aphasie. 1897.
  • Dysostosis cléido-crânienne héréditaire. Paul Sainton (1868-1958). 1897.
  • Rhizomelic spondylosis. 1898.
  • La pratique neurologie. Paris, Masson et Cie 1911
  • Paget's bone disease. Add. with André Léri. In Handbook of Neurology. Volume 4, Berlin, 1913.
  • Note on un syndrome de paralysie flasque plus ou moins généralisée avec abolition des reflexes, hyperalbuminose massive et xantochromie vers la guerison et de nature indéterminée. Add. with C. Chatelin. Revue neurologique, 1916, 30: 564-565.
  • Neurology. 2 volumes; Paris, 1923.
  • Travaux et mémoires. Paris, Masson et Cie 1926 and 1928.

further reading

Individual evidence

  1. www.ling.fju.edu.tw: Pierre Marie .