Marie-Foix-Alajouanine Syndrome

Classification according to ICD-10
R27.0	Ataxia, unspecified
ICD-10 online (WHO version 2019)

The Marie-Foix-Alajouanine syndrome , Latin atrophia cerebellaris tardiva type Marie-Foix-Alajouanine , describes a cerebellar- related ataxia in adulthood, often following alcohol abuse .

It should not be confused with the Foix-Alajouanine syndrome , which is a congenital malformation of the spinal vessels.

It is a degeneration of the cerebellum and olive with the clinical picture of progressive cerebellar ataxia, loss of cognition and chorea .

Apparently there is a genetic subgroup with an autosomal dominant inheritance .

The name refers to the authors of the first description from 1922 by Pierre Marie , Charles Foix and Théophile Alajouanine .

literature

F. Trebini, A. Appiotti, G. Scarzella: Atrofia cerebellare corticale tardiva di Pierre Marie, Foix ed Alajouanine. Descrizione di un caso clinico. In: Minerva medica. Vol. 81, No. 4, April 1990, pp. 315-317, ISSN 0026-4806 . PMID 2342656 .
AE Harding: "Idiopathic" late onset cerebellar ataxia. A clinical and genetic study of 36 cases. In: Journal of the Neurological Sciences. Vol. 51, No. 2, August 1981, pp. 259-271, ISSN 0022-510X . PMID 7276977 .
H. Kulawik: [Clinical aspects of late predominantly cortical Marie-Foix-Alajouanine cerebellar atrophy]. In: Psychiatry, Neurology, and Medical Psychology. Vol. 23, No. 11, November 1971, pp. 629-634, ISSN 0033-2739 . PMID 5145540 .
R. Burian, E. Armentsoudis: About a case of Atrophia cerebellaris tardiva of the Marie-Foix-Alajouanine type. In: Wiener Zeitschrift für Nervenheilkunde and its border areas. Vol. 28, No. 3, September 1970, pp. 185-195, ISSN 0043-5384 . PMID 4249372 .
P. KISSEL, G. ARNOULD, P. TRIDON, M. LAXENAIRE: [APROPOS OF 7 CASES OF LATE CORTICAL CEREBELLAR ATROPHY OF PIERRE-MARIE FOIX AND ALAJOUANINE TYPE]. In: Annales médicales de Nancy. Vol. 60, February 1963, pp. 261-280, ISSN 0003-4460 . PMID 14117711 .

Individual evidence

^ RB Richter: Late cortical cerebellar atrophy. A form of hereditary cerebellar ataxia. In: American Journal of Human Genetics , Vol. 2, No. 1, March 1950, pp. 1-29, ISSN 0002-9297 . PMID 15425502 . PMC 1716363 (free full text). Chicago, 1950, 2: 1-29.
^ P. Marie, C. Foix, T. Alajouanine: De l'atrophie cérébelleuse tardive à prédominance corticale. In: Revue neurologique , Paris, 1922, vol. 38, pp. 849-885 and pp. 1082-1111.
↑ Who named it

[1] RB Richter: Late cortical cerebellar atrophy. A form of hereditary cerebellar ataxia. In: American Journal of Human Genetics , Vol. 2, No. 1, March 1950, pp. 1-29, ISSN 0002-9297 . PMID 15425502 . PMC 1716363 (free full text). Chicago, 1950, 2: 1-29.

[2] P. Marie, C. Foix, T. Alajouanine: De l'atrophie cérébelleuse tardive à prédominance corticale. In: Revue neurologique , Paris, 1922, vol. 38, pp. 849-885 and pp. 1082-1111.

[3] Who named it