Chorea (medicine)

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Classification according to ICD-10
G25.4 drug-induced chorea
G25.5 other chorea
ICD-10 online (WHO version 2019)

The chorea (also chorea is called), a symptom of several diseases, the basal ganglia affect the brain. Typical are (predominantly in the waking state) involuntary, sudden, rapidly occurring, irregular movements of the extremities, face, neck and trunk, which occur both at rest and during voluntary movements.


The term chorea comes from the Greek word "c (h) oreia" ('dance'). With this, Plato called a choir dance consisting of dance, but also dances of madmen, with "Chorea insaniens". The expression was also introduced into medical nomenclature by Paracelsus in the 16th century for the "St. Vitus dance". Sydenham described chorea minor as a pathological mass phenomenon in the 17th century.

In 1872, George Huntington described chorea major as hereditary chorea. Overall, however, the descriptions were very inconsistent, and it was only with the advent of neuropathology and later genetics that the various forms were more precisely distinguished.

Definition of terms

Choreatic movement disorders belong to the large group of extrapyramidal hyperkinesias , which also include tremor , dystonia , ballism or tics in Tourette's syndrome . All extrapyramidal hyperkinesias are based on a malfunction of certain parts of the basal ganglia.

The Chorea (Greek for dance) is not a disease but a purely descriptive term for a symptom, the number of very different causes may underlie. The end result, however, is always a functional disorder of the striatum , which then leads to very characteristic movement disorders .


A distinction must be made between:


and possibly still

Determination of heavy metals in serum and / or urine

Web links

Individual evidence

  1. "B. Holdorff: Historical Aspects of basal ganglia disorders and movement disorders. In: Neurology journal for interdisciplinary training.. Volume 34, May 2015, pp 335-342.
  2. Barbara I. Tshisuaka: Dubini, Angelo. In: Werner E. Gerabek , Bernhard D. Haage, Gundolf Keil , Wolfgang Wegner (eds.): Enzyklopädie Medizingeschichte. De Gruyter, Berlin / New York 2005, ISBN 3-11-015714-4 , p. 324.