Blood serum

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Among blood serum , also briefly only serum (from latin serum , whey called ') is understood as the liquid portion of the blood which is obtained as a supernatant when a coagulated blood sample centrifuged .

This supernatant contains up to the power consumed by the clotting coagulation factors all naturally dissolved in the blood fluid substances. The blood serum corresponds to the blood plasma minus the coagulation factors (especially fibrin or fibrinogen). Due to the presence of bilirubin , the serum is yellowish in color.

The physiological serum osmolarity (isotonicity) in humans is 281–297 mosmol / l.

It contains 91% water and 7% protein . Protein proportions are: 62% albumin (reserve protein ) and the various globulins such as:

  • 3% α1-globulins (lipid transport)
  • 7% α2-globulins (iron transport, copper transport)
  • 9% β-globulins (iron transport, lipid transport)
  • 17% γ-globulins (immune defense)

The remaining 2% are electrolytes , nutrients , waste (such as urea ) and hormones .


  • Jan Behrends, Josef Bischofberger, Rainer Deutzmann: Physiology. (= Dual row). 1st edition. Thieme, Stuttgart 2010, ISBN 978-3-13-138411-9 .

Individual evidence

  1. Renate Wahrig-Burfeind (Ed.): True. Illustrated dictionary of the German language . ADAC-Verlag, Munich 2004, ISBN 3-577-10051-6 , pp. 787 .
  2. Peter Karlson: Short textbook of biochemistry for physicians and natural scientists. 12th edition. Georg Thieme Verlag, Stuttgart / New York 1984, ISBN 3-13-357812-X , p. 387.