Grandpa

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Opi stands for:

a term for the grandfather, see grandparents
Opi (Abruzzo) , town in the Italian region of Abruzzo
Opi (weapon) , weapon in the Philippines

OPI stands for:

Open Prepress Interface , interface protocol for prepress

OPI stands for:

Open Payment Initiative , standardization of the application interface between a till application and any solution for cashless payment
Order of Perpetual Indulgence , part of a global AIDS prevention organization
Oremus pro invicem as the end of a letter ("we pray for one another")

Opi is a ship name:

Opi (ship, 1966)

See also:

Opie