Organomegaly

As organomegaly refers to the abnormal, often morbid , enlargement of one or more organs .

There are separate names for certain organs that are abnormally enlarged. For example, in an enlarged liver a hepatomegaly , an enlarged heart a cardiomegaly and an enlarged spleen, a splenomegaly before. It is not an independent clinical picture, but a secondary organ change, the cause of which is another underlying disease.

In the POEMS syndrome ( polyneuropathy , organomegaly, endocrinopathy , monoclonal gammopathy , skin changes), several organs show abnormal enlargements.

The cause of the abnormal organ enlargement are often autoimmune diseases or metabolic diseases such as Gaucher's disease or Fabry's disease .

Individual evidence

1. ↑ S. Kuwabara, A. Dispenzieri et al. a .: Treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M-protein, and skin changes) syndrome. In: Cochrane database of systematic reviews. Number 4, 2008, p. CD006828, ISSN  1469-493X . doi: 10.1002 / 14651858.CD006828.pub2 . PMID 18843731 . (Review).
2. ↑ wisegeek.com: What Is Organomegaly? Retrieved October 3, 2011
3. ↑ Organomegaly. In: Orphanet (Rare Disease Database).
4. ↑ C. Kampmann, FA Baehner a. a .: The right ventricle in Fabry disease. In: Acta paediatrica. Volume 94, Number 447, March 2005, pp. 15-18, ISSN  0803-5326 . PMID 15895706 .