Peteosthor
Peteosthor was the trade name of an experimental drug from Buchler & Co (Braunschweig), which was used in German hospitals against tuberculosis and Bechterew's disease on patients from 1945–1956 . It was a mixture of the radioactive alpha emitter Radium -224 ( "Thorium-X") with colloidal platinum and the dye eosin , of the bath Pyrmonter been developed Lungenfacharzt Paul Troch and inserted under his direction in two hospitals in Bad Pyrmont and Heidelberg was. The ionizing radiation should accumulate in the inflammatory lesions and inhibit the inflammation or kill the tuberculosis bacteria. After initially sensational success reports, it soon turned out that there was no healing effect and that the patients were threatened with serious side effects instead. The long-term studies on the treated patients showed cancer rates increased many times over, and in the children there were also severe growth disorders of the skeleton.
Sources and individual references
- Heinz Spiess: Long-term study over more than 60 years: radiation damage caused by radium-224. In: Dtsch Arztebl. 110 (33-34), 2013, pp. A-1556 / B-1372 / C-1351.
- ↑ Peak not yet reached - With atomic energy against Tbc. In: Der Spiegel. May 3, 1947.
- ↑ R. Wilde: Peteosthor and Thorium X as a therapeutic agent for Bechterew's disease. In: AOTS. 1952, doi: 10.1007 / BF00414953 .
- ↑ CJ Tietz, H. Spiess: About the inhibitory effect of Peteosthor and its components on the growth of human tubercle bacteria in vitro. In: Clinical weekly. 1950, doi: 10.1007 / BF01486045
- ↑ The lucky grip - Not yielded. In: Der Spiegel. February 7, 1948.
- ^ H. Spiess: Peteosthor - a medical disaster due to Radium-224. In: Radiation and Environmental Biophysics 2002, doi: 10.1007 / s00411-002-0165-4 .