Pineoblastoma

As Pineoblastoma or pinealoblastoma a very rare malignant will Brain referred to, which according to the WHO classification of tumors of the central nervous system is classified as grade IV. Pineoblastomas are particularly common in children and young adults; the median age at diagnosis is 18 years.

The pineoblastoma, which is located in the area of ​​the pineal gland (glandula pinealis), is clinically noticeable, among other things, through double vision and vertical paralysis ( Parinaud's syndrome ) and disorders of the liquor outflow ( hydrocephalus ); It is not uncommon for tumor cells to spread along the inner fluid spaces of the brain and spinal cord. Reliable statements about the prognosis are not possible in view of the rarity of the tumor; in a frequently cited study the five-year survival rate is given as 58%.

In contrast to pineoblastoma, pineocytoma is a benign tumor (grade I WHO) which, like other tumors of the pineal region ( e.g. papillary tumor of the pineal region , pineal parenchymal tumor of intermediate differentiation, or germinoma ) must be differentiated in the neuropathological examination .

literature

• Nakazato et al .: Pineoblastoma. In: Louis et al. (Ed.): WHO Classification of Tumors of the Central Nervous System. IARC Press, Lyon 2007, ISBN 978-92-832-2430-3 .

Individual evidence

1. ^ SE Schild, BW Scheithauer, PJ Schomberg, CC Hook, PJ Kelly, L. Frick, JS Robinow, SJ Buskirk: Pineal parenchymal tumors. Clinical, pathologic, and therapeutic aspects. In: Cancer. 1993; 72 (3), pp. 870-880. PMID 8334641

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !