Pluripotency
As pluripotent (from Latin plus lat "more" and. Potentia "wealth, power") refers to stem cells that have the ability to cells of the three germ layers ( ectoderm , endoderm , mesoderm ) and the germline development of an organism. You can differentiate to any cell type of an organism, as they are not yet fixed to any specific tissue type. However, in contrast to totipotent stem cells, they are no longer able to form an entire organism, since pluripotent cells cannot form extraembryonic tissue .
Sometimes the terms totipotent and pluripotent are not clearly distinguished from one another. From the word's origin, however, totipotent means "all wealthy" and pluripotent means "more wealthy".
More recently, pluripotent (or at least multipotent ) stem cells have been isolated from a wide variety of human tissues. Bone marrow and umbilical cord blood are the primary sources for isolation and medical reuse. Research on stem cells promises ways to combat many diseases, but is also controversial from an ethical point of view. In a more recent approach, somatic cells are returned to a state of pluripotency by means of transfection . For more information on stem cell research, see the articles on stem cells and induced pluripotent stem cells .
Web links
Individual evidence
- ↑ Pamina Pflegerl, Thomas Keller, Brigitte Hantusch, Thomas Sören Hoffmann, Lukas Kenner: Stem Cell Research - Status, Outlook and Bioethical Aspect . In: Wiener Medical Wochenschrift . tape 158 , no. 17-18 , September 2008, ISSN 0043-5341 , p. 493–502 , doi : 10.1007 / s10354-008-0551-x ( springer.com [accessed October 4, 2018]).