Smallpox epidemic in Boston 1721

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In his work An Historical Account of the Small-pox Inoculated in New England , the doctor Zabdiel Boylston describes his view of the events

The Boston smallpox epidemic in 1721 marked the first viral epidemic in North America that used vaccination to contain the disease.

Between April and December 1721 5.889 inhabitants of diseased Boston to smallpox and 844 people died. At that time, it was not generally known that the use of weakened smallpox viruses triggers an immune response, but usually not a disease. In the course of the epidemic, a heated controversy arose over variolation , a vaccination with attenuated live viruses, which focused on the Puritan preacher Cotton Mather and the doctor William Douglass .

The dispute was mainly carried out in the press, with the New England Courant of James Franklin , Benjamin Franklin's brother , mobilizing the anti-vaccine group . Doctor Zabdiel Boylston alone vaccinated a total of 287 patients, including many prominent Boston citizens.

In various writings, the news of the events in Boston and the vaccination dispute that had flared up was also spread in England and other parts of Europe. This led to an increasing number of anti-vaccination users and a temporary decline in vaccination practice in London in the late 1720s.

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Individual evidence

  1. M. Best et al .: Making the right decision: Benjamin Franklin's son dies of smallpox in 1736 . In: Quality & Safety in Health Care . tape 16 , no. 6 , December 2007, pp. 478-480 , doi : 10.1136 / qshc.2007.023465 , PMID 18055894 , PMC 2653186 (free full text).