Prothoracotropic hormone
| Silkworm prothoracotropic hormone ( Bombyx mori ) | ||
|---|---|---|
| Mass / length primary structure | 109 amino acids | |
| Precursor | (187 aas) | |
| Isoforms | Homodimer | |
| Identifier | ||
| External IDs | ||
| Occurrence | ||
| Parent taxon | insects | |
The prothoracotropic hormone ( PTTH ) is an insect hormone . From a chemical point of view, it is a homodimer of two peptide chains , each consisting of 109 amino acids . It was first described in 1922 by Stefan Kopeć as a brain hormone .
PTTH is released from two groups of cells in the brain of insect larvae. As a glandotropic hormone , it controls the secretion of the steroid hormone ecdysone and thus growth and metamorphosis of the animal.
Individual evidence
- ↑ S. Nagata, H. Kataoka, A. Suzuki: Silk moth neuropeptide hormones: prothoracicotropic hormone and others. In: Annals of the New York Academy of Sciences . Volume 1040, April 2005, pp. 38-52, ISSN 0077-8923 . doi : 10.1196 / annals.1327.004 . PMID 15891004 .
- ^ Stefan Kopeć: Studies on the Necessity of the Brain for the Inception of Insect Metamorphosis . In: Biol Bull . tape 42 , no. 6 , 1922, pp. 323–342 ( Free full text [PDF]).
- ↑ A. Mizoguchi, S. Ohsumi, K. Kobayashi, N. Okamoto, N. Yamada, K. Tateishi, Y. Fujimoto, H. Kataoka: Prothoracicotropic hormone acts as a neuroendocrine switch between pupal diapause and adult development. In: PloS one. Volume 8, number 4, 2013, p. E60824, ISSN 1932-6203 . doi : 10.1371 / journal.pone.0060824 . PMID 23577167 . PMC 3618418 (free full text).