Regulatory genes

from Wikipedia, the free encyclopedia

As a regulatory gene in which is genetics a gene denotes that that gene expression controls. These include genes for activators or for repressors . In contrast to regulatory genes, structural genes code for enzymes and structural proteins .

A regulatory gene codes either for an active repressor, which only becomes inactive in the presence of a certain substrate ( inducer ), such as e.g. B. the lactose operon , or it codes for an inactive repressor, which only becomes active in the presence of a certain product , such as. B. the tryptophan operon . An example of an activator is the catabolite activator protein in catabolite repression .

Individual evidence

  1. ^ Robert C. King: A Dictionary of Genetics. OUP USA, 2013, ISBN 978-0-199-76644-4 , p. 401.
  2. ↑ TW Lee, KW Southern: Topical cystic fibrosis transmembrane conductance regulator gene replacement for cystic fibrosis-related lung disease. In: The Cochrane database of systematic reviews. Volume 11, 2013, pp. CD005599, ISSN  1469-493X . doi : 10.1002 / 14651858.CD005599.pub4 . PMID 24282073 .
  3. ^ R. Perniola: Expression of the autoimmune regulator gene and its relevance to the mechanisms of central and peripheral tolerance. In: Clinical & developmental immunology. Volume 2012, 2012, pp. 207403, ISSN  1740-2530 . doi : 10.1155 / 2012/207403 . PMID 23125865 . PMC 3485510 (free full text).