Recombination frequency
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The recombination frequency , also called recombination frequency (symbol θ), is a term of genetics and a measure of the frequency with which gene coupling takes place. By definition, the recombination frequency shows the probability that a crossing-over will take place between two genes in meiosis . It thus indicates whether the genes in question belong to the same coupling group. With a recombination frequency of 50% or more, it can be assumed that the respective genes are not linked to one another.
Because of the definition of recombination frequency, it is also closely related to the genetic proximity between two genes. A recombination frequency of 0.01 corresponds to a distance of one centimorgan when mapping the genes . The measurements or descriptions of the distance between two genes based on this mostly underestimate this distance. This depends on the increased probability of a double (or any even number) crossing-over. This genetic proximity does not necessarily correspond to the spatial proximity.
Individual verification
- ↑ recombination. Retrieved October 9, 2019 .
- ↑ Genetic Recombination and Gene Mapping | Learn Science at Scitable. Retrieved October 21, 2019 .
- ^ Griffiths, Anthony JF: An introduction to genetic analysis . 7th ed. WH Freeman, New York 2000, ISBN 0-7167-3520-2 .
- ^ Griffiths, Anthony JF: An introduction to genetic analysis . 7th ed. WH Freeman, New York 2000, ISBN 0-7167-3520-2 .