Rheumatoid nodules

from Wikipedia, the free encyclopedia
Classification according to ICD-10
M06.3- Rheumatoid nodules
ICD-10 online (WHO version 2019)

In rheumatoid nodules is nodes that lie under the skin and typical of the Rheumatoid arthritis : (synonym Rheumatoid arthritis are).

Occur

In the course of the disease, they usually arise in places of increased pressure load, especially on the extensor side of joints, most often on the elbow. Rheumatoid nodules are usually a sign of severe disease. Since more and more patients with rheumatoid arthritis are treated earlier with long-acting anti - inflammatory drugs , the severe forms of rheumatoid arthritis have become rarer. An unexplained observation is the isolated occurrence of rheumatoid nodules during treatment of rheumatoid arthritis with methotrexate .

Rheumatoid nodules occur in about 20 percent of all patients with rheumatoid arthritis. In a good 40 percent of cases, there is vasculitis in the connective tissue .

Rheumatoid nodules are more common in patients with positive rheumatoid factor .

The size of the rheumatoid nodules is variable and depends on the activity of the disease process. The administration of cortisol usually reduces the size of the rheumatic nodules. They are involved in the genesis of bursitis , tendinitis , cardiac and nodular pulmonary manifestations, scleritis and CNS manifestations.

literature

  • Hans-Jürgen Hettenkofer (Ed. :) Rheumatology: Diagnostics, Clinic, Therapy. Thieme, Stuttgart 2003. ISBN 3-13-657805-8 .
  • Wolfgang Miehle (Ed.): Rheumatology in practice and clinic. Thieme, Stuttgart 2000. ISBN 3-13-701102-7 .
  • Henning Zeidler , Beat A. Michel: Differential diagnosis of rheumatic diseases. Springer Science & Business Media, 2008. ISBN 978-3-540-76773-2 .

Individual evidence

  1. ↑ a b Hettenkofer: Rheumatology. P. 67
  2. ↑ Ute Donhauser-Gruber, Alfred AJ Gruber: Rheuma. Examination and treatment of inflammatory rheumatic diseases. Thieme, Stuttgart 2013. ISBN 978-3-13-170341-5 . P. 32
  3. ↑ a b Miehle: Rheumatology in practice and clinic. P. 463
  4. ^ Association for Orthopedic Rheumatology (Ed.): Rheumaorthopädie. Springer, 2006. ISBN 978-3-79851589-5 . P. 31