Risk Characterization Ratio

The term Risk Characterization Ratio ( RCR for short ) comes from the context of Regulation (EC) No. 1907/2006 (REACH).

As part of the substance assessment, the registrant / distributor (manufacturer or importer) must carry out the hazard assessment for a substance , whereby it must also be examined whether the substance is to be classified as PBT or vPvB . In addition, threshold values for the environment and human health must be derived. For the environment, the effective threshold than that PNEC value ( english predicted no-effect concentration ), ie the concentration of the substance in the environment, are to be expected in any harmful effects defined. To human health is considered in accordance with the DNEL value ( english derived no-effect level ). Can be specified for substances for which no DNEL how mutagenic substances without a lower limit by the DMEL ( English Derived Minimal Effect Level ).

For substances that are classified as dangerous or those with PBT or vPvB properties, has the expected environmental concentration in an exposure assessment also PEC ( English Predicted Environmental Concentration ) can be estimated. The risk ratio RCR (Risk Characterization Ratio) for the environment is then calculated from the PEC and PNEC in the risk assessment as follows:

{\ displaystyle RCR = {\ frac {PEC} {PNEC}}}

Similarly, the RCR for human health can be calculated from the exposure limit value, such as the air limit value, and the DNEL value:

{\ displaystyle RCR = {\ frac {Exposition} {DNEL}}}

If the RCR is greater than one, there is a risk in using the substance. In such a case, the hazard or exposure assessment must be reviewed and / or the possible emissions reduced by additional technical measures until the safe use of the substance can be ensured.

Web links

Regulation (EC) No. 1907/2006 , original version of the REACH regulation with changes
Regulation (EC) No. 440/2008 laying down test methods according to Regulation (EC) No. 1907/2006 (REACH)
When is a substance a PBT or a vPvB substance? In: reachhelpdesk.at. September 3, 2013, accessed April 6, 2019 .

Individual evidence

↑ ^a ^b Chemical Safety Assessment (CSA). In: Umweltbundesamt.de. May 19, 2016, accessed April 6, 2019 .
↑ ^a ^b ^c Guidance on Information Requirements and Chemical Safety Assessment. (PDF) Part E: Risk Characterization. In: ECHA . May 2016, p. 8 , accessed on April 6, 2019 (English).

[UBA-1] Chemical Safety Assessment (CSA). In: Umweltbundesamt.de. May 19, 2016, accessed April 6, 2019 .

[ECHAguideV3.0-2] Guidance on Information Requirements and Chemical Safety Assessment. (PDF) Part E: Risk Characterization. In: ECHA . May 2016, p. 8 , accessed on April 6, 2019 (English).