Sago spleen

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The term Sagomilz describes a pathologically altered spleen , the macroscopically at Sago , a product of granulated starch , recalls.

A sago spleen is an expression of focal amyloidosis of the spleen follicles, where extracellular glycoproteins in filamentary structure and beta-sheet storage are deposited. These proteins are mostly of the AA type and are caused by all types of chronic inflammation.

Demarcation

A distinction is made between systemic and localized amyloidoses. In typical generalized amyloidoses, the spleen can be affected in two forms, either with amyloid deposits in the area of ​​the follicles or with deposits diffuse in the red pulp (parenchyma of the spleen). According to its macroscopic aspect, the former is called sago spleen, the latter ham spleen.

Individual evidence

  1. Herwig Hamperl: Pathological-histological internship . Springer-Verlag, July 2, 2013, ISBN 978-3-662-05507-6 , p. 108.