Septicemia
| Classification according to ICD-10 | |
|---|---|
| A41.9 | Sepsis, unspecified |
| ICD-10 online (WHO version 2019) | |
With septicemia is referred to the total infection of the human or animal body caused by bacteria or toxins caused in the blood.
It is a more severe form of bacteremia when sepsis occurs .
It arises from the permanent or periodic penetration of bacteria and their poisons from a source of disease into the bloodstream ( blood poisoning ) with a simultaneous failure of the normal defense against pathogens. It often occurs during or after acute or chronic local infectious disease when the pathogens enter the bloodstream directly , e.g. B. as wound sepsis .
In the past, terms such as sepsis, septicemia and sepsis syndrome were defined very differently, which led to unclear epidemiological data, contradicting results from clinical studies and, as a result, therapeutic recommendations.
In 1991, Roger C. Bone attempted to create a uniform definition of the clinical picture, with the aim of recognizing patients as septic at an early stage and determining risk factors for the development of a septic event as soon as the patient was admitted. The "Consensus Conference" of 1991 , carried out by the "American College of Chest Physicians" and the "Society of Critical Care Medicine", has since recommended that the expression "septicemia", which was previously used, neither in everyday clinical practice nor in the design of clinical studies continue to use.
Individual evidence
- ↑ Alphabetical directory for the ICD-10-WHO version 2019, volume 3. German Institute for Medical Documentation and Information (DIMDI), Cologne, 2019, p. 800
- ↑ Members of the American College of Chest Physicians / Society of Critical Care Medicine Consensus Conference Committee: American College of Chest Physicians / Society of Critical Care Medicine Consensus Conference: definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. In: Critical Care Medicine, Vol. 20 ,. No. 6, June 1992, pp. 864-874. PMID 1597042 .
