Stereo electroencephalography

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Stereoelectroencephalography ( sEEG ) describes the procedure to derive EEG signals from deep electrodes after or during stereotactic brain surgery . This recording method is used in the treatment of patients with drug-resistant epilepsy or Parkinson's disease . The aim is to determine the underlying neural causes in the course of "pre-surgical" diagnostics. Electrodes are surgically implanted in the brain tissue by a neurosurgeon. In the case of epilepsy, the aim is to identify the region of the brain that can be assumed to be the origin of the epileptic seizures. This region is then surgically removed in another operation if necessary. In the case of Parkinson's disease that is otherwise treatment-resistant, however, sEEG is used to determine the stimulation parameters in the context of deep brain stimulation .

This technique was first used in the detailed diagnosis of epilepsy patients in the second half of the 20th century at the Hôpital Sainte-Anne in Paris. Intracerebral electrodes are placed in the target area to record electrical activity during epileptic seizures. This contributes to the exact delimitation of the "epileptogenic zone". This is the region that is the cause of the seizures. In further treatment, an operative resection of this area can lead to complete freedom from seizures. About one percent of the patients who are examined using sEEG have a serious adverse event (for example cerebral hemorrhage or infection of the affected tissue ) which can lead to permanent neurological impairment or death. For this reason, sEEG is only used in exceptional cases of otherwise therapy-resistant disease courses.

Individual evidence

  1. ↑ J. Talairach, J. Bancaud, G. Szikla, et al .: Approche nouvelle de la neurosurgery de l'epilepsie. Méthodologie stérérotaxique et résultats thérapeutiques (= Neurosurgery. 20, Suppl. 1). Masson, Paris 1974, pp. 1-240.
  2. ↑ M. Cossu, F. Cardinale, L. Castana, et al .: Stereoelectroencephalography in the presurgical evaluation of focal epilepsy. A retrospective analysis of 215 procedures . In: Neurosurgery . tape 57 , no. 4 , 2005, p. 706-718 , PMID 16239883 .