Strachan's Syndrome

The Strachan syndrome is a rare, by disturbances of vision and peripheral nerve disease marked. Degeneration of the optic nerve ( optic atrophy) and polyneuropathy occur, and hearing disorders, dizziness and skin symptoms (urogenital ulcerative dermatitis) have also been described. It is probably a combined deficiency disease, with thiamine (vitamin B1) deficiency playing the main role, as is the case with beriberi and Wernicke encephalopathy . In addition, essential amino acids and cobalamins (vitamin B12) are missing . Strachan's syndrome was first described in 1897 and is limited to a few areas in Africa and Asia where cassava is the main food source. The hydrocyanic acid contained in manioc may also play a role.

literature

• Marianne Dieterich, Stefan Lorenzl: Vitamin metabolism disorders. In: Thomas Brandt, Johannes Dichgans and Hans Christoph Diener (eds.): Therapy and course of neurological diseases. 5th edition, Kohlhammer, Stuttgart 2007, ISBN 978-3-17-019074-0 .

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !