Structural motif

In biochemistry, a structural motif describes a set of two or more secondary structures in biopolymers with functional significance or part of a protein domain . Structural motifs in proteins are mostly conserved and indicate a partial functional similarity of proteins with the same structural motif.

Examples of structural motifs in proteins are the omega loop , the zinc finger , the helix-turn-helix motif , the CSK ₄ motif , the nest motif and the niche motif .

literature

CO Mackenzie, G. Grigoryan: Protein structural motifs in prediction and design. In: Current opinion in structural biology. Volume 44, June 2017, pp. 161–167, doi : 10.1016 / j.sbi.2017.03.012 , PMID 28460216 , PMC 5513761 (free full text).

Individual evidence

↑ John Kuriyan: The Molecules of Life: Physical and Chemical Principles. Garland Science, 2012, ISBN 978-1-135-08892-7 , p. 151.
^ Ruchi Singh: Bioinformatics: Genomics and Proteomics. Vikas Publishing House, 2015, ISBN 978-9-325-97855-3 , p. 230.
↑ Florent Masseglia: Successes and New Directions in Data Mining. Idea Group Inc (IGI), 2008, ISBN 978-1-599-04645-7 .

[Kuriyan-1] John Kuriyan: The Molecules of Life: Physical and Chemical Principles. Garland Science, 2012, ISBN 978-1-135-08892-7 , p. 151.

[Singh-2] Ruchi Singh: Bioinformatics: Genomics and Proteomics. Vikas Publishing House, 2015, ISBN 978-9-325-97855-3 , p. 230.

[Masseglia-3] Florent Masseglia: Successes and New Directions in Data Mining. Idea Group Inc (IGI), 2008, ISBN 978-1-599-04645-7 .