Summation (neurophysiology)

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Under summation means the settlement ( integration ) of arriving in the nerve cell nerve impulses that are either an excitatory (excitatory) or inhibitory (inhibitory) effect on the occurrence of an action potential may have. The incoming exciting or inhibiting potentials ( EPSP or IPSP ) are summed up spatially and temporally:

  • Spatial summation: If excitatory or inhibitory potentials arrive at the neuron from several synapses at the same time , these are summed up, whereby an action potential occurs on the axon hill if the sum of the incoming potentials exceeds a threshold value.
  • Temporal summation: If a single synapse encounters several exciting or inhibiting potentials in the neuron at sufficiently short intervals, these are also summed up and when a certain threshold value is exceeded, an action potential is created on the axon hill.

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