Tübingen cake

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The Tübinger Torte is a method of 3D histology .

Healing from skin cancer is only guaranteed if the tumor has been completely removed. With the method called Tübinger Torte , surgery and diagnosis are combined so that even very small tumor extensions can be detected. The tumor is cut out as a round disc with a small safety margin. The three-dimensional cut edges are then prepared in such a way that they are completely visible in histological sections. The cut edges of the cut-out tissue can be identified by a thread marking.

The skin is incised in a circle perpendicular to the skin surface. The angle between the perpendicular cut and the plane of the entire base should be 90 °. The point of the specimen pointing towards the skull (i.e. the most cranial point) is marked with a thread. From this point the edge of the entire specimen is cut off in a clockwise direction and cut into several narrow segments of approximately the same size. Usually these individual fragments contain epidermis, dermis and adipose tissue. Parallel cuts are made perpendicular to the epidermal plane. From this the entire depth of the preparation can be assessed.

The base and sides of the removed tissue are examined microscopically during the operation with a 250-fold magnification for freedom from tumors. The histological section must not show either tumor tissue or severe inflammation. If there is evidence of tumor remnants, targeted follow-up surgery can be carried out. If tumor extensions can still be seen at one point, recuts are specifically made, in exceptional cases up to four or five times. The procedure takes about ten minutes and is performed under computer-controlled local anesthesia.

This method can be operated on in a tissue-conserving and tissue-saving manner. The three-dimensional, fine tissue examination results in a more than 99% chance of discovering all tumor remnants.

The method was published in a study by Professor Helmut Breuninger from the University Dermatology Clinic in Tübingen and perfected to the point that it can be routinely used. Almost 5000 patients, some with very extensive basal cell carcinomas , have already been treated with 3D histology.

Individual evidence

  1. 3D histology protects against relapses of basalioma. “Slicing of the Tübinger Torte” was perfected in Tübingen. Another advantage: good cosmetic results.
  2. ^ Hatice Beckering: Rapid section diagnosis in malignant tumors of the skin.
  3. Laser Clinic Dres. Steinert GmbH. ( Memento of the original from February 3, 2015 in the Internet Archive ) Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice. @1@ 2Template: Webachiv / IABot / www.dres-steinert.de
  4. FC Eberle, W. Schippert, B. Trilling, M. Röcken, H. Breuninger: Cosmetic results of histographically controlled excision of non-melanoma skin cancer in the head and neck region . In: Journal of the German Dermatological Society , 2005, Volume 3: pp. 109–112.