Platelet concentrate
A platelet concentrate (TC) is a medical product that is obtained from human blood ( blood product ). It is used to compensate for a lack of blood platelets ( thrombocytes ) in the patient through transfusion . These play a key role in blood clotting .
There are three types of platelet concentrates:
- Pooled leukocyte-depleted platelet concentrate
- Leukocyte-depleted apheresis platelet concentrate
- Irradiated platelet concentrate
A storage temperature of +22 ° C ± 2 ° C must be maintained for all platelet concentrates. During storage, constant agitation must be ensured, storage being as short as possible, but not longer than a maximum of five days after donation.
Various causes (e.g. also drugs) or clinical pictures can lead to a lack of thrombocytes, so-called thrombocytopenia . If the number of platelets falls below a certain lower limit (50,000 / µl), this can lead to insatiable bleeding after injuries or during operations. An even further decrease in the number of these platelets (<10,000 / µl) ultimately also causes spontaneous bleeding, i. H. Bleeding without any external cause. For example, before operations or when there is a risk of spontaneous bleeding, these patients can be prophylactically transfused with platelet concentrates.
Web links
- Guidelines for the collection of blood and blood components and for the use of blood products (haemotherapy) - Second guideline amendment 2010 (PDF) German Medical Association; accessed on February 21, 2014
- Expert opinion on the value of platelet preparations (PDF; 257 kB) Berufsverband Deutscher Transfusionsmediziner e. V.
