Trigger mechanism

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The trigger mechanism is a bacterial- mediated invasion process into eukaryotic cells. A type III secretion system is used to inject mediators into the host cell, which induce actin polymerization and depolymerization or membrane protuberances and ultimately lead to the uptake of the bacterium. The pathogenic salmonella and shigella use the trigger mechanism to invade.

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Javier Pizarro-Cerda, Pascale Cossart: Bacterial Adhesion and Entry into Host Cells .Cell 124, 715-727, February 24, 2006. doi : 10.1016 / j.cell.2006.02.012