Vacanti mouse
The Vacanti mouse was a laboratory mouse ( SCID ) that was used as a bioreactor to grow cartilage tissue in the shape of a human auricle . The chondrocytes (cartilage cells) came from cattle and were sown in a form whose shape is modeled on a human ear and which is degradable. This was then implanted under the skin of the nude mouse .
The "ear mouse"
The "ear mouse" was created by pioneers of tissue engineering (Engl. Tissue engineering ), the brothers Charles and Joseph Vacanti and their team of Boston and Cambridge in the Department of Anesthesiology of the University of Massachusetts Medical School grown. The results of the experiment were published in 1997.
controversy
The photo of the Vacanti mouse was circulated in the press and on the Internet; often by email without much text. Therefore, it was unclear to many whether the photo was real or a hoax . In the late 1990s, the photo was used as a symbol in protest against genetic engineering (although no transgenic organisms were produced here).
Individual evidence
- ↑ Yilin Cao, Joseph P. Vacanti, Keith T. Paige, Joseph Upton, Charles A. Vacanti: Transplantation of chondrocytes utilizing a polymer-cell construct to produce tissue-engineered cartilage in the shape of a human ear . In: Plastic and reconstructive surgery . tape 100 , no. 2 , 1997, p. 297-302 (discussion pp. 303-304).
- ↑ # 8 Vacanti Ear Mouse. (No longer available online.) Archived from the original on August 12, 2014 ; Retrieved August 4, 2014 . Info: The archive link was inserted automatically and has not yet been checked. Please check the original and archive link according to the instructions and then remove this notice.
