Winter bottom sign

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The Winterbottom sign , a painless lymph node swelling in the dorsal-lateral neck area, is considered to be the leading symptom of African trypanosomiasis (sleeping sickness).

This disease has three stages. In the second stage, the so-called "hemolymphatic stage", the Winterbottom sign typically occurs alongside other symptoms such as headache and fever. Depending on the form of the disease, this can happen after a few days (East African form), or only after weeks or months (West African form). These lymph node swellings are a sign of the spread of the pathogens in the lymphatic system. The winter bottom sign can last for several months.

The term comes from the author Thomas Masterman Winterbottom (1766-1859) around 1803.

Individual evidence

  1. ^ Roche Lexicon Medicine. Urban & Fischer, Hoffmann-La Roche SA (Basel), Edition: 5, 2003, ISBN 3-437-15150-9 .
  2. sleeping sickness. ( Memento from October 2, 2008 in the web archive archive.today ) on: aerzte-ohne-grenzen.de , last seen on April 26, 2009.
  3. TM Winterbottom: An account of the native Africans in the neighborhood of Sierra Leone. C. Whittingham, London 1803.