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Importing Wikidata short description: "Protein-coding gene in the species Homo sapiens" (Shortdesc helper) |
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{{Short description|Protein-coding gene in the species Homo sapiens}} |
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{{Infobox_gene}} |
{{Infobox_gene}} |
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| title = Entrez Gene: Solute carrier family 22 member 13 |
| title = Entrez Gene: Solute carrier family 22 member 13 |
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| url = https://www.ncbi.nlm.nih.gov/gene/9390 |
| url = https://www.ncbi.nlm.nih.gov/gene/9390 |
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| access-date = 2017-10-05 |
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*{{cite journal |vauthors=Bahn A, Hagos Y, Reuter S, Balen D, Brzica H, Krick W, Burckhardt BC, Sabolic I, Burckhardt G |title=Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13) |journal=J. Biol. Chem. |volume=283 |issue=24 |pages=16332–41 |year=2008 |pmid=18411268 |doi=10.1074/jbc.M800737200 |
*{{cite journal |vauthors=Bahn A, Hagos Y, Reuter S, Balen D, Brzica H, Krick W, Burckhardt BC, Sabolic I, Burckhardt G |title=Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13) |journal=J. Biol. Chem. |volume=283 |issue=24 |pages=16332–41 |year=2008 |pmid=18411268 |doi=10.1074/jbc.M800737200 |doi-access=free }} |
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*{{cite journal |vauthors=Irshad S, Mahul-Mellier AL, Kassouf N, Lemarie A, Grimm S |title=Isolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers |journal=Cell Death Differ. |volume=16 |issue=6 |pages=890–8 |year=2009 |pmid=19282870 |pmc=2683172 |doi=10.1038/cdd.2009.21 |
*{{cite journal |vauthors=Irshad S, Mahul-Mellier AL, Kassouf N, Lemarie A, Grimm S |title=Isolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers |journal=Cell Death Differ. |volume=16 |issue=6 |pages=890–8 |year=2009 |pmid=19282870 |pmc=2683172 |doi=10.1038/cdd.2009.21 }} |
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*{{cite journal |vauthors=Tzvetkov MV, Vormfelde SV, Balen D, Meineke I, Schmidt T, Sehrt D, Sabolić I, Koepsell H, Brockmöller J |title=The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin |journal=Clin. Pharmacol. Ther. |volume=86 |issue=3 |pages=299–306 |year=2009 |pmid=19536068 |doi=10.1038/clpt.2009.92 |s2cid=8583867 |
*{{cite journal |vauthors=Tzvetkov MV, Vormfelde SV, Balen D, Meineke I, Schmidt T, Sehrt D, Sabolić I, Koepsell H, Brockmöller J |title=The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin |journal=Clin. Pharmacol. Ther. |volume=86 |issue=3 |pages=299–306 |year=2009 |pmid=19536068 |doi=10.1038/clpt.2009.92 |s2cid=8583867 }} |
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*{{cite journal |vauthors=Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR |title=Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score |journal=Mol. Med. |volume=16 |issue=7–8 |pages=247–53 |year=2010 |pmid=20379614 |pmc=2896464 |doi=10.2119/molmed.2009.00159 |
*{{cite journal |vauthors=Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR |title=Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score |journal=Mol. Med. |volume=16 |issue=7–8 |pages=247–53 |year=2010 |pmid=20379614 |pmc=2896464 |doi=10.2119/molmed.2009.00159 }} |
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*{{cite journal |vauthors=Schulz C, Fork C, Bauer T, Golz S, Geerts A, Schömig E, Gründemann D |title=SLC22A13 catalyses unidirectional efflux of aspartate and glutamate at the basolateral membrane of type A intercalated cells in the renal collecting duct |journal=Biochem. J. |volume=457 |issue=2 |pages=243–51 |year=2014 |pmid=24147638 |doi=10.1042/BJ20130654 |
*{{cite journal |vauthors=Schulz C, Fork C, Bauer T, Golz S, Geerts A, Schömig E, Gründemann D |title=SLC22A13 catalyses unidirectional efflux of aspartate and glutamate at the basolateral membrane of type A intercalated cells in the renal collecting duct |journal=Biochem. J. |volume=457 |issue=2 |pages=243–51 |year=2014 |pmid=24147638 |doi=10.1042/BJ20130654 }} |
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*{{cite journal |vauthors=AbuAli G, Chaisaklert W, Stelloo E, Pazarentzos E, Hwang MS, Qize D, Harding SV, Al-Rubaish A, Alzahrani AJ, Al-Ali A, Sanders TA, Aboagye EO, Grimm S |title=The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis |journal=Oncogene |volume=34 |issue=13 |pages=1718–28 |year=2015 |pmid=24769897 |pmc=4119473 |doi=10.1038/onc.2014.93 |
*{{cite journal |vauthors=AbuAli G, Chaisaklert W, Stelloo E, Pazarentzos E, Hwang MS, Qize D, Harding SV, Al-Rubaish A, Alzahrani AJ, Al-Ali A, Sanders TA, Aboagye EO, Grimm S |title=The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis |journal=Oncogene |volume=34 |issue=13 |pages=1718–28 |year=2015 |pmid=24769897 |pmc=4119473 |doi=10.1038/onc.2014.93 }} |
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{{refend}} |
{{refend}} |
Latest revision as of 07:34, 27 March 2022
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Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
Aliases | SLC22A13, OAT10, OCTL1, OCTL3, ORCTL-3, ORCTL3, solute carrier family 22 member 13 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 604047 MGI: 2143107 HomoloGene: 3140 GeneCards: SLC22A13 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Solute carrier family 22 member 13 is a protein that in humans is encoded by the SLC22A13 gene. [5]
Function[edit]
This gene encodes a member of the organic-cation transporter family. It is located in a gene cluster with another member of the family, organic cation transporter like 4. The encoded protein is a transmembrane protein involved in the transport of small molecules. This protein can function to mediate urate uptake and is a high affinity nicotinate exchanger in the kidneys and the intestine.
References[edit]
- ^ a b c GRCh38: Ensembl release 89: ENSG00000172940 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000074028 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Entrez Gene: Solute carrier family 22 member 13". Retrieved 2017-10-05.
Further reading[edit]
- Bahn A, Hagos Y, Reuter S, Balen D, Brzica H, Krick W, Burckhardt BC, Sabolic I, Burckhardt G (2008). "Identification of a new urate and high affinity nicotinate transporter, hOAT10 (SLC22A13)". J. Biol. Chem. 283 (24): 16332–41. doi:10.1074/jbc.M800737200. PMID 18411268.
- Irshad S, Mahul-Mellier AL, Kassouf N, Lemarie A, Grimm S (2009). "Isolation of ORCTL3 in a novel genetic screen for tumor-specific apoptosis inducers". Cell Death Differ. 16 (6): 890–8. doi:10.1038/cdd.2009.21. PMC 2683172. PMID 19282870.
- Tzvetkov MV, Vormfelde SV, Balen D, Meineke I, Schmidt T, Sehrt D, Sabolić I, Koepsell H, Brockmöller J (2009). "The effects of genetic polymorphisms in the organic cation transporters OCT1, OCT2, and OCT3 on the renal clearance of metformin". Clin. Pharmacol. Ther. 86 (3): 299–306. doi:10.1038/clpt.2009.92. PMID 19536068. S2CID 8583867.
- Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
- Schulz C, Fork C, Bauer T, Golz S, Geerts A, Schömig E, Gründemann D (2014). "SLC22A13 catalyses unidirectional efflux of aspartate and glutamate at the basolateral membrane of type A intercalated cells in the renal collecting duct". Biochem. J. 457 (2): 243–51. doi:10.1042/BJ20130654. PMID 24147638.
- AbuAli G, Chaisaklert W, Stelloo E, Pazarentzos E, Hwang MS, Qize D, Harding SV, Al-Rubaish A, Alzahrani AJ, Al-Ali A, Sanders TA, Aboagye EO, Grimm S (2015). "The anticancer gene ORCTL3 targets stearoyl-CoA desaturase-1 for tumour-specific apoptosis". Oncogene. 34 (13): 1718–28. doi:10.1038/onc.2014.93. PMC 4119473. PMID 24769897.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.