MT-ATP8: Difference between revisions
Content deleted Content added
Gene encoded in the mitochondrial genome |
Separate protein and gene sections |
||
| Line 57: | Line 57: | ||
| CDD = |
| CDD = |
||
}} |
}} |
||
| ⚫ | |||
==The protein== |
|||
| ⚫ | This subunit appears to be an integral component of the stator stalk in [[Saccharomyces cerevisiae|yeast]] [[mitochondrial]] [[F-ATPase]]s.<ref name="pmid12626501">{{cite journal | author = Stephens AN, Khan MA, Roucou X, Nagley P, Devenish RJ | title = The molecular neighborhood of subunit 8 of yeast mitochondrial F1F0-ATP synthase probed by cysteine scanning mutagenesis and chemical modification | journal = J. Biol. Chem. | volume = 278 | issue = 20 | pages = 17867–75 |date=May 2003 | pmid = 12626501 | doi = 10.1074/jbc.M300967200 | url = }}</ref> The stator stalk is anchored in the [[membrane]], and acts to prevent futile rotation of the ATPase subunits relative to the rotor during coupled ATP synthesis/hydrolysis. This subunit may have an analogous function in [[Metazoa |
||
| ⚫ | |||
| ⚫ | This [[protein]] subunit appears to be an integral component of the stator stalk in [[Saccharomyces cerevisiae|yeast]] [[mitochondrial]] [[F-ATPase]]s.<ref name="pmid12626501">{{cite journal | author = Stephens AN, Khan MA, Roucou X, Nagley P, Devenish RJ | title = The molecular neighborhood of subunit 8 of yeast mitochondrial F1F0-ATP synthase probed by cysteine scanning mutagenesis and chemical modification | journal = J. Biol. Chem. | volume = 278 | issue = 20 | pages = 17867–75 |date=May 2003 | pmid = 12626501 | doi = 10.1074/jbc.M300967200 | url = }}</ref> The stator stalk is anchored in the [[membrane]], and acts to prevent futile rotation of the ATPase subunits relative to the rotor during coupled ATP synthesis/hydrolysis. This subunit may have an analogous function in [[Metazoa]]. |
||
Subunit 8 differs in [[sequence (biology)|sequence]] between Metazoa, [[plants]] and [[fungus|Fungi]]. |
|||
==The gene== |
|||
The ATP synthase protein 8 of human and other mammals is encoded in the [[mitochondrial genome]] by the ''MT-ATP8'' [[gene]]. |
|||
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. --> |
<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. --> |
||
Revision as of 12:51, 27 January 2016
| ATP synthase protein 8 (metazoa) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | ATP-synt_8 | ||||||||
| Pfam | PF00895 | ||||||||
| Pfam clan | CL0255 | ||||||||
| InterPro | IPR001421 | ||||||||
| |||||||||
| Plant ATP synthase F0 subunit 8 | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | YMF19 | ||||||||
| Pfam | PF02326 | ||||||||
| Pfam clan | CL0255 | ||||||||
| InterPro | IPR003319 | ||||||||
| |||||||||
| Fungal ATP synthase protein 8 (A6L) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| Symbol | Fun_ATP-synt_8 | ||||||||
| Pfam | PF05933 | ||||||||
| Pfam clan | CL0255 | ||||||||
| InterPro | IPR009230 | ||||||||
| |||||||||
The protein
ATP synthase protein 8 is a subunit of mitochondrial ATP synthase.
This protein subunit appears to be an integral component of the stator stalk in yeast mitochondrial F-ATPases.[1] The stator stalk is anchored in the membrane, and acts to prevent futile rotation of the ATPase subunits relative to the rotor during coupled ATP synthesis/hydrolysis. This subunit may have an analogous function in Metazoa.
Subunit 8 differs in sequence between Metazoa, plants and Fungi.
The gene
The ATP synthase protein 8 of human and other mammals is encoded in the mitochondrial genome by the MT-ATP8 gene.
References
- ^ Stephens AN, Khan MA, Roucou X, Nagley P, Devenish RJ (May 2003). "The molecular neighborhood of subunit 8 of yeast mitochondrial F1F0-ATP synthase probed by cysteine scanning mutagenesis and chemical modification". J. Biol. Chem. 278 (20): 17867–75. doi:10.1074/jbc.M300967200. PMID 12626501.
{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)
Further reading
 | This protein-related article is a stub. You can help Wikipedia by expanding it. |