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Revision as of 13:41, 27 January 2016 by Manudouz(talk | contribs)(Synonymy: MT-ATP8 = URF A6L)
This protein subunit appears to be an integral component of the stator stalk in yeastmitochondrialF-ATPases.[1] The stator stalk is anchored in the membrane, and acts to prevent futile rotation of the ATPase subunits relative to the rotor during coupled ATP synthesis/hydrolysis. This subunit may have an analogous function in Metazoa.
The ATP synthase protein 8 of human and other mammals is encoded in the mitochondrial genome by the MT-ATP8gene. When the complete human mitochondrial genome was first published, the MT-ATP8 gene was described as the unidentified reading frameURF A6L.[2]