Boswellia serrata

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Boswellia serrata
in Kinnerasani Wildlife Sanctuary, Andhra Pradesh, India.
Scientific classification Edit this classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Rosids
Order: Sapindales
Family: Burseraceae
Genus: Boswellia
Species:
B. serrata
Binomial name
Boswellia serrata

Boswellia serrata is a plant that produces Indian frankincense. It is also known as Indian oli-banum, Salai guggul, and Sallaki in Sanskrit.[1] The plant is native to India.


Research and usage

Extracts of Boswellia serrata have been clinically studied for osteoarthritis and joint function, with the research showing trends of benefit (slight improvement) in pain and function, warranting further investigation.[2] Positive effects of Boswellia in some chronic inflammatory diseases including rheumatoid arthritis, bronchial asthma, ulcerative colitis and Crohn's disease have been reported.[3] It has been used in Indian traditional medicine for diabetes.[4]

Topical application

Boswellia serrata is used in the manufacture of the anti-wrinkle agent "Boswelox",[5] which has been criticised as being ineffective.[6]

Active constituents

Boswellia serrata contains chemical constituents mainly β-boswellic acid, acetyl-β-boswellic acid, 11-keto-β-boswellic acid and acetyl-11-keto-β-boswellic acid.[7] Among boswellic acids, acetyl-11-keto-β-boswellic acid (AKBA) is the most potent in vitro inhibitor of 5-lipoxygenase.[8][9]

References

  1. ^ Pole, Sebastian (2013) Ayurvedic Medicine: The Principles of Traditional Practice. Singing Dragon Press. p.179
  2. ^ Cameron, M; Chrubasik, S (May 22, 2014). "Oral herbal therapies for treating osteoarthritis". Cochrane Summaries. Retrieved June 6, 2014.
  3. ^ Ammon, HP (2010). "Modulation of the immune system by Boswellia serrata extracts and boswellic acids". Phytomedicine. 17 (11): 862–7. doi:10.1016/j.phymed.2010.03.003. PMID 20696559.
  4. ^ Mehrzadi, S.; Tavakolifar, B.; Huseini, H. F.; Mosavat, S. H.; Heydari, M. (2018). "The Effects of Boswellia serrata Gum Resin on the Blood Glucose and Lipid Profile of Diabetic Patients: A Double-Blind Randomized Placebo-Controlled Clinical Trial". Journal of Evidence-Based Integrative Medicine. 23: 2515690X18772728. doi:10.1177/2515690X18772728. PMC 5960856. PMID 29774768.
  5. ^ Wrinkle breakthrough claim from L'Oreal
  6. ^ L'Oreal slammed over cream claims
  7. ^ Dragos, Dorin; Gilca, Marilena; Gaman, Laura; Vlad, Adelina; Iosif, Liviu; Stoian, Irina; Lupescu, Olivera (2017-01-16). "Phytomedicine in Joint Disorders". Nutrients. 9 (1): 70. doi:10.3390/nu9010070. ISSN 2072-6643. PMC 5295114. PMID 28275210.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  8. ^ Siddiqui, M. Z. (May 2011). "Boswellia serrata, a potential antiinflammatory agent: an overview 7". Indian Journal of Pharmaceutical Sciences. 73 (3): 255–261. doi:10.4103/0250-474X.93507 (inactive 2018-11-07). PMC 3309643. PMID 22457547.{{cite journal}}: CS1 maint: DOI inactive as of November 2018 (link) CS1 maint: unflagged free DOI (link)
  9. ^ Meka, B. Z. (Feb 2017). "Synthesis of new analogs of AKBA and evaluation of their anti-inflammatory activities 7". Bioorganic & Medicinal Chemistry. 25 (4): 1374–1388. doi:10.1016/j.bmc.2016.12.045. PMID 28110820.