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== Education ==
== Education ==
Grossman received a Bachelor of Science in Biochemistry from [[Brown University]] in 1979. He earned his Ph.D at the [[University of Wisconsin–Madison]] in 1984.<ref>{{Cite web|title=Alan D. Grossman|url=https://biology.mit.edu/profile/alan-d-grossman/|access-date=2022-02-05|website=MIT Department of Biology|language=en-US}}</ref> Grossman completed a postdoctoral fellowship in the Department of Cellular and Developmental Biology at [[Harvard University]] before joining MIT's biology department in 1988.<ref name=":0">{{Cite web|title=Alan D. Grossman named head of the Department of Biology|url=https://news.mit.edu/2014/alan-grossman-biology-department-head-0804|access-date=2022-02-05|website=MIT News {{!}} Massachusetts Institute of Technology|language=en}}</ref>
Grossman received a Bachelor of Science in biochemistry from [[Brown University]] in 1979. He earned his Ph.D. at the [[University of Wisconsin–Madison]] in 1984.<ref>{{Cite web|title=Alan D. Grossman|url=https://biology.mit.edu/profile/alan-d-grossman/|access-date=2022-02-05|website=MIT Department of Biology|language=en-US}}</ref> Grossman completed a postdoctoral fellowship in the Department of Cellular and Developmental Biology at [[Harvard University]] before joining MIT's biology department in 1988.<ref name=":0">{{Cite web|title=Alan D. Grossman named head of the Department of Biology|url=https://news.mit.edu/2014/alan-grossman-biology-department-head-0804|access-date=2022-02-05|website=MIT News {{!}} Massachusetts Institute of Technology|language=en}}</ref>


==Career==
==Career==
Grossman has served as head of the MIT's department of biology since 2014, when he succeeded [[Tania A. Baker]].<ref name=":0" />
Grossman has served as head of the MIT's department of biology since 2014, when he succeeded [[Tania A. Baker]].<ref name=":0" />


Initially, his research was focused on characterization of bacterial [[chromosome segregation]]. His group was among the first that identified the Spo0J protein, the [[Homology (chemistry)|homologue]] of [[ParABS system|ParB]], responsible for the process of chromosome segregation in [[B. subtilis]].<ref name="pmid8071208">{{cite journal| author=Ireton K, Gunther NW, Grossman AD| title=spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis. | journal=J Bacteriol | year= 1994 | volume= 176 | issue= 17 | pages= 5320–9 | pmid=8071208 | doi=10.1128/jb.176.17.5320-5329.1994 | pmc=196717 }} </ref> He later moved on to show that Spo0J binds to specific cis-sites on the DNA in order to implement its function and identified the sequences of those cis-sites which was termed ''[[ParABS system|ParS]]''.<ref name="pmid9506522">{{cite journal| author=Lin DC, Grossman AD| title=Identification and characterization of a bacterial chromosome partitioning site. | journal=Cell | year= 1998 | volume= 92 | issue= 5 | pages= 675–85 | pmid=9506522 | doi=10.1016/s0092-8674(00)81135-6 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9506522 | hdl=1721.1/83851 | s2cid=11402267 | hdl-access=free }} </ref>
Initially, his research was focused on characterization of bacterial [[chromosome segregation]]. His group was among the first that identified the Spo0J protein, the [[Homology (chemistry)|homologue]] of [[ParABS system|ParB]], responsible for the process of chromosome segregation in [[B. subtilis]].<ref name="pmid8071208">{{cite journal| author=Ireton K, Gunther NW, Grossman AD| title=spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis. | journal=J Bacteriol | year= 1994 | volume= 176 | issue= 17 | pages= 5320–9 | pmid=8071208 | doi=10.1128/jb.176.17.5320-5329.1994 | pmc=196717 }}</ref> He later moved on to show that Spo0J binds to specific cis-sites on the DNA in order to implement its function and identified the sequences of those cis-sites which was termed ''[[ParABS system|ParS]]''.<ref name="pmid9506522">{{cite journal| author=Lin DC, Grossman AD| title=Identification and characterization of a bacterial chromosome partitioning site. | journal=Cell | year= 1998 | volume= 92 | issue= 5 | pages= 675–85 | pmid=9506522 | doi=10.1016/s0092-8674(00)81135-6 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9506522 | hdl=1721.1/83851 | s2cid=11402267 | hdl-access=free }}</ref>


In 2006, Grossman received a life-saving [[Heart transplantation|heart transplant]]. He has discussed the experience publicly and encouraged others to consider [[organ donation]].<ref>{{Cite web|title=Alan Grossman shares lessons learned from his lifesaving gift|url=https://science.mit.edu/alan-grossman-shares-lessons-learned-from-his-lifesaving-gift/|access-date=2022-02-05|website=MIT School of Science|language=en-US}}</ref>
In 2006, Grossman received a life-saving [[Heart transplantation|heart transplant]]. He has discussed the experience publicly and encouraged others to consider [[organ donation]].<ref>{{Cite web|title=Alan Grossman shares lessons learned from his lifesaving gift|url=https://science.mit.edu/alan-grossman-shares-lessons-learned-from-his-lifesaving-gift/|access-date=2022-02-05|website=MIT School of Science|language=en-US}}</ref>
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[[Category:Massachusetts Institute of Technology School of Science faculty]]
[[Category:Massachusetts Institute of Technology School of Science faculty]]
[[Category:Members of the United States National Academy of Sciences]]
[[Category:Members of the United States National Academy of Sciences]]
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[[Category:Brown University alumni]]
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[[Category:University of Wisconsin–Madison alumni]]




{{US-biologist-stub}}
{{US-biologist-stub}}
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[[Category:Brown University alumni]]
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[[Category:University of Wisconsin–Madison alumni]]

Revision as of 09:02, 21 October 2022

Not to be confused with Allen Grossman.
Alan D. Grossman
Alma mater
AwardsEli Lilly and Company-Elanco Research Award (1997)
Scientific career
InstitutionsMassachusetts Institute of Technology

Alan D. Grossman, is an American microbiologist; he is currently the Praecis Professor of Biology and head of the Department of Biology at the Massachusetts Institute of Technology. He is a member of the National Academy of Sciences and the American Academy of Arts & Sciences.[1][2]

Education

Grossman received a Bachelor of Science in biochemistry from Brown University in 1979. He earned his Ph.D. at the University of Wisconsin–Madison in 1984.[3] Grossman completed a postdoctoral fellowship in the Department of Cellular and Developmental Biology at Harvard University before joining MIT's biology department in 1988.[4]

Career

Grossman has served as head of the MIT's department of biology since 2014, when he succeeded Tania A. Baker.[4]

Initially, his research was focused on characterization of bacterial chromosome segregation. His group was among the first that identified the Spo0J protein, the homologue of ParB, responsible for the process of chromosome segregation in B. subtilis.[5] He later moved on to show that Spo0J binds to specific cis-sites on the DNA in order to implement its function and identified the sequences of those cis-sites which was termed ParS.[6]

In 2006, Grossman received a life-saving heart transplant. He has discussed the experience publicly and encouraged others to consider organ donation.[7]

References

  1. ^ "Alan D. Grossman". www.nasonline.org. Retrieved 2022-02-05.
  2. ^ "Alan D. Grossman". American Academy of Arts & Sciences. Retrieved 2022-02-05.
  3. ^ "Alan D. Grossman". MIT Department of Biology. Retrieved 2022-02-05.
  4. ^ a b "Alan D. Grossman named head of the Department of Biology". MIT News | Massachusetts Institute of Technology. Retrieved 2022-02-05.
  5. ^ Ireton K, Gunther NW, Grossman AD (1994). "spo0J is required for normal chromosome segregation as well as the initiation of sporulation in Bacillus subtilis". J Bacteriol. 176 (17): 5320–9. doi:10.1128/jb.176.17.5320-5329.1994. PMC 196717. PMID 8071208.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  6. ^ Lin DC, Grossman AD (1998). "Identification and characterization of a bacterial chromosome partitioning site". Cell. 92 (5): 675–85. doi:10.1016/s0092-8674(00)81135-6. hdl:1721.1/83851. PMID 9506522. S2CID 11402267.
  7. ^ "Alan Grossman shares lessons learned from his lifesaving gift". MIT School of Science. Retrieved 2022-02-05.

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