MT-ATP8: Difference between revisions

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*{{cite journal |vauthors=Torroni A, Achilli A, Macaulay V, etal |title=Harvesting the fruit of the human mtDNA tree. |journal=Trends Genet. |volume=22 |issue= 6 |pages= 339–45 |year= 2006 |pmid= 16678300 |doi= 10.1016/j.tig.2006.04.001 }}
*{{cite journal | author=Bodenteich A, Mitchell LG, Polymeropoulos MH, Merril CR |title=Dinucleotide repeat in the human mitochondrial D-loop. |journal=Hum. Mol. Genet. |volume=1 |issue= 2 |pages= 140 |year= 1993 |pmid= 1301157 |doi=10.1093/hmg/1.2.140-a }}
*{{cite journal | author=Bodenteich A, Mitchell LG, Polymeropoulos MH, Merril CR |title=Dinucleotide repeat in the human mitochondrial D-loop. |journal=Hum. Mol. Genet. |volume=1 |issue= 2 |pages= 140 |year= 1993 |pmid= 1301157 |doi=10.1093/hmg/1.2.140-a }}
*{{cite journal | author=Lu X, Walker T, MacManus JP, Seligy VL |title=Differentiation of HT-29 human colonic adenocarcinoma cells correlates with increased expression of mitochondrial RNA: effects of trehalose on cell growth and maturation. |journal=Cancer Res. |volume=52 |issue= 13 |pages= 3718–25 |year= 1992 |pmid= 1377597 |doi= }}
*{{cite journal | author=Lu X, Walker T, MacManus JP, Seligy VL |title=Differentiation of HT-29 human colonic adenocarcinoma cells correlates with increased expression of mitochondrial RNA: effects of trehalose on cell growth and maturation. |journal=Cancer Res. |volume=52 |issue= 13 |pages= 3718–25 |year= 1992 |pmid= 1377597 |doi= }}
*{{cite journal | author=Marzuki S, Noer AS, Lertrit P, ''et al.'' |title=Normal variants of human mitochondrial DNA and translation products: the building of a reference data base. |journal=Hum. Genet. |volume=88 |issue= 2 |pages= 139–45 |year= 1992 |pmid= 1757091 |doi= 10.1007/bf00206061}}
*{{cite journal |vauthors=Marzuki S, Noer AS, Lertrit P, etal |title=Normal variants of human mitochondrial DNA and translation products: the building of a reference data base. |journal=Hum. Genet. |volume=88 |issue= 2 |pages= 139–45 |year= 1992 |pmid= 1757091 |doi= 10.1007/bf00206061}}
*{{cite journal | author=Moraes CT, Andreetta F, Bonilla E, ''et al.'' |title=Replication-competent human mitochondrial DNA lacking the heavy-strand promoter region. |journal=Mol. Cell. Biol. |volume=11 |issue= 3 |pages= 1631–7 |year= 1991 |pmid= 1996112 |doi= | pmc=369459 }}
*{{cite journal |vauthors=Moraes CT, Andreetta F, Bonilla E, etal |title=Replication-competent human mitochondrial DNA lacking the heavy-strand promoter region. |journal=Mol. Cell. Biol. |volume=11 |issue= 3 |pages= 1631–7 |year= 1991 |pmid= 1996112 |doi= | pmc=369459 }}
*{{cite journal | author=Attardi G, Chomyn A, Doolittle RF, ''et al.'' |title=Seven unidentified reading frames of human mitochondrial DNA encode subunits of the respiratory chain NADH dehydrogenase. |journal=Cold Spring Harb. Symp. Quant. Biol. |volume=51 |issue= 1|pages= 103–14 |year= 1987 |pmid= 3472707 |doi= 10.1101/sqb.1986.051.01.013}}
*{{cite journal |vauthors=Attardi G, Chomyn A, Doolittle RF, etal |title=Seven unidentified reading frames of human mitochondrial DNA encode subunits of the respiratory chain NADH dehydrogenase. |journal=Cold Spring Harb. Symp. Quant. Biol. |volume=51 |issue= 1|pages= 103–14 |year= 1987 |pmid= 3472707 |doi= 10.1101/sqb.1986.051.01.013}}
*{{cite journal | author=Chomyn A, Cleeter MW, Ragan CI, ''et al.'' |title=URF6, last unidentified reading frame of human mtDNA, codes for an NADH dehydrogenase subunit. |journal=Science |volume=234 |issue= 4776 |pages= 614–8 |year= 1986 |pmid= 3764430 |doi=10.1126/science.3764430 }}
*{{cite journal |vauthors=Chomyn A, Cleeter MW, Ragan CI, etal |title=URF6, last unidentified reading frame of human mtDNA, codes for an NADH dehydrogenase subunit. |journal=Science |volume=234 |issue= 4776 |pages= 614–8 |year= 1986 |pmid= 3764430 |doi=10.1126/science.3764430 }}
*{{cite journal | author=Chomyn A, Mariottini P, Cleeter MW, ''et al.'' |title=Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase. |journal=Nature |volume=314 |issue= 6012 |pages= 592–7 |year= 1985 |pmid= 3921850 |doi=10.1038/314592a0 }}
*{{cite journal |vauthors=Chomyn A, Mariottini P, Cleeter MW, etal |title=Six unidentified reading frames of human mitochondrial DNA encode components of the respiratory-chain NADH dehydrogenase. |journal=Nature |volume=314 |issue= 6012 |pages= 592–7 |year= 1985 |pmid= 3921850 |doi=10.1038/314592a0 }}
*{{cite journal | author=Anderson S, Bankier AT, Barrell BG, ''et al.'' |title=Sequence and organization of the human mitochondrial genome. |journal=Nature |volume=290 |issue= 5806 |pages= 457–65 |year= 1981 |pmid= 7219534 |doi=10.1038/290457a0 }}
*{{cite journal |vauthors=Anderson S, Bankier AT, Barrell BG, etal |title=Sequence and organization of the human mitochondrial genome. |journal=Nature |volume=290 |issue= 5806 |pages= 457–65 |year= 1981 |pmid= 7219534 |doi=10.1038/290457a0 }}
*{{cite journal | author=Montoya J, Ojala D, Attardi G |title=Distinctive features of the 5'-terminal sequences of the human mitochondrial mRNAs. |journal=Nature |volume=290 |issue= 5806 |pages= 465–70 |year= 1981 |pmid= 7219535 |doi=10.1038/290465a0 }}
*{{cite journal | author=Montoya J, Ojala D, Attardi G |title=Distinctive features of the 5'-terminal sequences of the human mitochondrial mRNAs. |journal=Nature |volume=290 |issue= 5806 |pages= 465–70 |year= 1981 |pmid= 7219535 |doi=10.1038/290465a0 }}
*{{cite journal | author=Horai S, Hayasaka K, Kondo R, ''et al.'' |title=Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue= 2 |pages= 532–6 |year= 1995 |pmid= 7530363 |doi=10.1073/pnas.92.2.532 | pmc=42775 }}
*{{cite journal |vauthors=Horai S, Hayasaka K, Kondo R, etal |title=Recent African origin of modern humans revealed by complete sequences of hominoid mitochondrial DNAs. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=92 |issue= 2 |pages= 532–6 |year= 1995 |pmid= 7530363 |doi=10.1073/pnas.92.2.532 | pmc=42775 }}
*{{cite journal | author=Rieder MJ, Taylor SL, Tobe VO, Nickerson DA |title=Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome. |journal=Nucleic Acids Res. |volume=26 |issue= 4 |pages= 967–73 |year= 1998 |pmid= 9461455 |doi=10.1093/nar/26.4.967 | pmc=147367 }}
*{{cite journal | author=Rieder MJ, Taylor SL, Tobe VO, Nickerson DA |title=Automating the identification of DNA variations using quality-based fluorescence re-sequencing: analysis of the human mitochondrial genome. |journal=Nucleic Acids Res. |volume=26 |issue= 4 |pages= 967–73 |year= 1998 |pmid= 9461455 |doi=10.1093/nar/26.4.967 | pmc=147367 }}
*{{cite journal | author=Andrews RM, Kubacka I, Chinnery PF, ''et al.'' |title=Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. |journal=Nat. Genet. |volume=23 |issue= 2 |pages= 147 |year= 1999 |pmid= 10508508 |doi= 10.1038/13779 }}
*{{cite journal |vauthors=Andrews RM, Kubacka I, Chinnery PF, etal |title=Reanalysis and revision of the Cambridge reference sequence for human mitochondrial DNA. |journal=Nat. Genet. |volume=23 |issue= 2 |pages= 147 |year= 1999 |pmid= 10508508 |doi= 10.1038/13779 }}
*{{cite journal | author=Ingman M, Kaessmann H, Pääbo S, Gyllensten U |title=Mitochondrial genome variation and the origin of modern humans. |journal=Nature |volume=408 |issue= 6813 |pages= 708–13 |year= 2001 |pmid= 11130070 |doi= 10.1038/35047064 }}
*{{cite journal | author=Ingman M, Kaessmann H, Pääbo S, Gyllensten U |title=Mitochondrial genome variation and the origin of modern humans. |journal=Nature |volume=408 |issue= 6813 |pages= 708–13 |year= 2001 |pmid= 11130070 |doi= 10.1038/35047064 }}
*{{cite journal | author=Finnilä S, Lehtonen MS, Majamaa K |title=Phylogenetic network for European mtDNA. |journal=Am. J. Hum. Genet. |volume=68 |issue= 6 |pages= 1475–84 |year= 2001 |pmid= 11349229 |doi=10.1086/320591 | pmc=1226134 }}
*{{cite journal | author=Finnilä S, Lehtonen MS, Majamaa K |title=Phylogenetic network for European mtDNA. |journal=Am. J. Hum. Genet. |volume=68 |issue= 6 |pages= 1475–84 |year= 2001 |pmid= 11349229 |doi=10.1086/320591 | pmc=1226134 }}
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*{{cite journal | author=Ingman M, Gyllensten U |title=Mitochondrial genome variation and evolutionary history of Australian and New Guinean aborigines. |journal=Genome Res. |volume=13 |issue= 7 |pages= 1600–6 |year= 2003 |pmid= 12840039 |doi= 10.1101/gr.686603 | pmc=403733 }}
}}
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Revision as of 17:11, 1 September 2015

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ATP synthase protein 8 (metazoa)
Identifiers
SymbolATP-synt_8
PfamPF00895
Pfam clanCL0255
InterProIPR001421
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Plant ATP synthase F0 subunit 8
Identifiers
SymbolYMF19
PfamPF02326
Pfam clanCL0255
InterProIPR003319
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Fungal ATP synthase protein 8 (A6L)
Identifiers
SymbolFun_ATP-synt_8
PfamPF05933
Pfam clanCL0255
InterProIPR009230
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary

ATP synthase protein 8 is an protein that in humans is encoded by the MT-ATP8 gene. It is a subunit of mitochondrial ATP synthase.

This subunit appears to be an integral component of the stator stalk in yeast mitochondrial F-ATPases.[1] The stator stalk is anchored in the membrane, and acts to prevent futile rotation of the ATPase subunits relative to the rotor during coupled ATP synthesis/hydrolysis. This subunit may have an analogous function in Metazoa. Subunit 8 differs in sequence between Metazoa, plants and fungi).

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References

  1. ^ Stephens AN, Khan MA, Roucou X, Nagley P, Devenish RJ (May 2003). "The molecular neighborhood of subunit 8 of yeast mitochondrial F1F0-ATP synthase probed by cysteine scanning mutagenesis and chemical modification". J. Biol. Chem. 278 (20): 17867–75. doi:10.1074/jbc.M300967200. PMID 12626501.{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)

Further reading

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This article incorporates text from the public domain Pfam and InterPro: IPR001421


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