Maximilian Nierenstein

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Maximilian Nierenstein
Born1877
Died1946
Alma materUniversity of Bristol
Known forNierenstein reaction
Scientific career
FieldsBiochemistry

Maximilian Nierenstein (also known as Moses Max Nierenstein or Max Nierenstein, born in 1877 - died in 1946) was a professor of biochemistry at the University of Bristol.

He is known for the Nierenstein reaction, an organic reaction describing the conversion of an acid chloride into an haloketone with diazomethane.

In 1912, Polish biochemist Casimir Funk isolated a complex of micronutrients and proposed the complex be named "vitamine" (a portmanteau of "vital amine") reportedly suggested by friend Max Nierenstein.[1][2]

He also studied natural phenols and tannins[3] found in different plant species. He showed in 1945 that luteic acid, a molecule present in the myrobalanitannin, a tannin found in the fruit of Terminalia chebula, is an intermediary compound in the synthesis of ellagic acid.[4] Working with Arthur George Perkin, he prepared ellagic acid from algarobilla and certain other fruits in 1905.[5]. He suggested its formation from galloyl-glycine by Penicillium in 1915.[6] Tannase is an enzyme that Niederstein used to produce m-digallic acid from gallotannins.[7] He proved the presence of catechin in cocoa beans in 1931.[8]

He also worked on milk and caseinogen.[9] He reviewed the discovery of lactose in 1936.[10]

Works

  • Synthese des 2-Oxyflavonols. Maximilian Nierenstein, 1904
  • Concerning the Treatment of Experimental Trypanosomiasis. Benjamin Moore, Maximilian Nierenstein and John Lancelot Todd, 1908
  • Chemie der Gerbstoffe. Maximilian Nierenstein, 1910
  • Organische Arsenverbindungen und ihre chemotherapeutische Bedeutung. Maximilian Nierenstein, 1913
  • Incunabula of Tannin Chemistry: A Coll. of Some Early Papers on the Chemistry Chemistry of the Tannins. Maximilian Nierenstein, 1932
  • The Natural Organic Tannins: History, Chemistry, Distribution. Maximilian Nierenstein and Macgregor Skene, 1934

References

  1. ^ Combs, Gerald. The vitamins: fundamental aspects in nutrition and health.
  2. ^ Funk, C. and H. E. Dubin. The Vitamines. Baltimore: Williams and Wilkins Company, 1922.
  3. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 16742048, please use {{cite journal}} with |pmid=16742048 instead.
  4. ^ The distribution of myrobalanitannin. Nierenstein M and Potter J, Biochem J. 1945, 39(5), pages 390-392, PMID 21020785
  5. ^ CXLI.—Some oxidation products of the hydroxybenzoic acids and the constitution of ellagic acid. Part I. Arthur George Perkin and Maximilian Nierenstein, J. Chem. Soc. Trans., 1905, 87, pages 1412-1430, doi:10.1039/CT9058701412
  6. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 16742368, please use {{cite journal}} with |pmid=16742368 instead.
  7. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 16744910, please use {{cite journal}} with |pmid=16744910 instead.
  8. ^ The Catechin Of The Cacao Bean. W. B. Adam, F. Hardy and M. Nierenstein, J. Am. Chem. Soc., 1931, 53 (2), pages 727–728, doi:10.1021/ja01353a041
  9. ^ The Action of Diazomethane on Caseinogen. Arthur Geake and Maximilian Nierenstein, Biochem J., 1914 August, 8(4), pages 287–292, PMC PMC1276579
  10. ^ The Discovery of Lactic Sugar. M. Nierenstein, Isis, February 1936, Volume 24, Number 2, pages 367-369 (Article)

External links