Pass Out of Existence and VIPoma: Difference between pages
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{{Infobox_Disease | |
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:''For other meanings see [[disappearance]].'' |
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Name = VIPoma | |
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{{Infobox Album | <!-- See Wikipedia:WikiProject_Albums --> |
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Image = | |
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Caption = | |
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DiseasesDB = 13877 | |
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ICD10 = {{ICD10|C|25|4|c|15}} or {{ICD10|E|16|8|e|15}} | |
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Cover = Chimaira_Pass_Out_of_Existance.jpg | |
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ICD9 = | |
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ICDO = 8155/3 | |
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Recorded = [[2001]] at Third Stone in [[North Hollywood]], [[California]] | |
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OMIM = | |
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MedlinePlus = 000228 | |
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Length = 62:30<br />66:31 (with Bonus Track) | |
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eMedicineSubj = med | |
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Label = [[Roadrunner Records]] | |
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eMedicineTopic = 2379 | |
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Producer = [[Andrew Murdock]] | |
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eMedicine_mult = {{eMedicine2|med|2399}} {{eMedicine2|ped|2428}} | |
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Reviews = |
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MeshID = D003969 | |
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* [[Allmusic]] {{Rating|4.5|5}} [http://www.allmusic.com/cg/amg.dll?p=amg&sql=10:jxfwxqt0ldje~T1 link] | |
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Last album = ''[[This Present Darkness (Chimaira album)|This Present Darkness ]]''<br />(2000) | |
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This album = '''''Pass out of Existence'''''<br />(2001) | |
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Next album = ''[[The Impossibility of Reason]]''<br />(2003) | |
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}} |
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A '''VIPoma''' (also known as '''Verner Morrison syndrome''', after the physicians who first described it <ref>Verner, J. V., and Morrison, A. B. Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemia. ''Am J Med'' 1958; '''374''': 1958.</ref>) is a rare (1 per 10,000,000 per year) [[endocrine]] [[tumor]],<ref name="urlDorlands Medical Dictionary:VIPoma">{{cite web |url=http://www.mercksource.com/pp/us/cns/cns_hl_dorlands_split.jsp?pg=/ppdocs/us/common/dorlands/dorland/nine/000116307.htm |title=Dorlands Medical Dictionary:VIPoma |format= |work= |accessdate=}}</ref> usually (about 90%) originating in the [[pancreas]], which produces [[vasoactive intestinal peptide]] (VIP). |
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'''''Pass out of Existence''''' is the debut studio album by [[Chimaira]], released on [[October 2]], [[2001]]. |
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A syndrome caused by [[non-β islet-cell]] tumors. |
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Some editions of the album include a hidden track at the end of "Jade", extending the track's total runtime to 13:57. The [[Japan]]ese/[[Australia]]n pressing includes the bonus track "Without Moral Restraint". |
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It may be associated with multiple endocrine neoplasia. |
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The massive amounts of VIP in turn cause profound and chronic '''w'''atery '''d'''[[diarrhea|iarrhea]] and resultant [[dehydration]], '''h'''[[hypokalemia|ypokalemia]], '''a'''[[achlorhydria|chlorhydria]] (hence '''WDHA-syndrome''', or '''pancreatic cholera syndrome'''), acidosis, [[vasodilation]] ([[flushing (physiology)|flushing]] and [[hypotension]]), [[hypercalcemia]] and [[hyperglycemia]].<ref>Mansour JC, Chen H. Pancreatic endocrine tumors. ''J Surg Res'' 2004; '''120''': 139-61. PMID 15172200</ref> |
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==Track listing== |
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# "Let Go" – 3:51 |
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# "Dead Inside" – 3:45 |
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# "Severed" – 3:16 |
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# "Lumps" – 3:54 |
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# "Pass out of Existence" – 3:24 |
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# "Abeo" – 1:44 |
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# "Split" – 3:12 |
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# "Painting the White to Grey" – 4:44 |
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# "Taste My..." – 4:02 |
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# "Rizzo" – 4:38 |
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# "Sphere" – 4:20 |
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# "Forced Life" – 3:48 |
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# "Options" – 3:50 |
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# "Jade" – 13:58 |
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# "Without Moral Restraint" – 4:02 [Bonus Track] |
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==Symptoms and Signs== |
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==Personnel== |
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The major clinical features are prolonged watery [[diarrhea]] (fasting stool volume > 750 to 1000 mL/day) and symptoms of [[hypokalemia]] and [[dehydration]]. |
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* [[Mark Hunter (musician)|Mark Hunter]] – [[Singing|vocals]] |
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Half of the patients have relatively constant [[diarrhea]] while the rest have alternating periods of severe and moderate [[diarrhea]]. |
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* [[Rob Arnold]] – [[Lead Guitar]] |
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One third have diarrhea < 1yr before diagnosis, but in 25%, diarrhea is present for 5 yr or more before diagnosis. |
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* Jason Hager – [[Rhythm Guitar]] |
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[[Lethargy]], muscle weakness, [[nausea]], vomiting and crampy abdominal pain are frequent symptoms. |
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* [[Jim LaMarca]] – [[Bass guitar|Bass]] |
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[[Hyperkalemia]] and impaired [[glucose]] tolerance occur in < 50% of patients. |
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* [[Andols Herrick]] – [[Drum kit|drums]] |
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During attacks of diarrhea, flushing similar to the [[carcinoid syndrome]] occur rarely. |
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* [[Chris Spicuzza]] – [[Programming (music)|Electronics]], [[Keyboard instrument|Keyboard]], [[Backup Vocals]] |
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==Diagnosis== |
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{{Chimaira}} |
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Besides the clinical picture, [[fasting]] VIP [[blood plasma|plasma]] dosage may confirm the diagnosis, and [[CT scan]] and [[somatostatin]] receptor [[scintigraphy]] are used to localise the [[tumor]], which is usually [[metastasis|metastatic]] at presentation. |
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==Treatment== |
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Besides treating the [[water]] and [[electrolyte]] abnormalities, [[octreotide]] (a [[somatostatin]] analogue) can be used to temper symptoms. [[Surgery]] is the only curative option. |
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[[Category:Debut albums]] |
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[[Category:Roadrunner Records albums]] |
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==References== |
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[[it:Pass Out of Existence]] |
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<references/> |
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| ⚫ | |||
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^The MERCK MANUAL Of Diagnosis And Therapy |
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{{oncology-stub}} |
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{{Tumor morphology}} |
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{{Endocrine gland neoplasia}} |
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[[de:Verner-Morrison-Syndrom]] |
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[[it:VIPoma]] |
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[[pl:Guz wydzielający VIP]] |
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Revision as of 20:37, 10 October 2008
| VIPoma | |
|---|---|
| Specialty | Endocrinology  |
A VIPoma (also known as Verner Morrison syndrome, after the physicians who first described it [1]) is a rare (1 per 10,000,000 per year) endocrine tumor,[2] usually (about 90%) originating in the pancreas, which produces vasoactive intestinal peptide (VIP).
A syndrome caused by non-β islet-cell tumors. It may be associated with multiple endocrine neoplasia.
The massive amounts of VIP in turn cause profound and chronic watery diarrhea and resultant dehydration, hypokalemia, achlorhydria (hence WDHA-syndrome, or pancreatic cholera syndrome), acidosis, vasodilation (flushing and hypotension), hypercalcemia and hyperglycemia.[3]
Symptoms and Signs
The major clinical features are prolonged watery diarrhea (fasting stool volume > 750 to 1000 mL/day) and symptoms of hypokalemia and dehydration. Half of the patients have relatively constant diarrhea while the rest have alternating periods of severe and moderate diarrhea. One third have diarrhea < 1yr before diagnosis, but in 25%, diarrhea is present for 5 yr or more before diagnosis. Lethargy, muscle weakness, nausea, vomiting and crampy abdominal pain are frequent symptoms. Hyperkalemia and impaired glucose tolerance occur in < 50% of patients. During attacks of diarrhea, flushing similar to the carcinoid syndrome occur rarely.
Diagnosis
Besides the clinical picture, fasting VIP plasma dosage may confirm the diagnosis, and CT scan and somatostatin receptor scintigraphy are used to localise the tumor, which is usually metastatic at presentation.
Treatment
Besides treating the water and electrolyte abnormalities, octreotide (a somatostatin analogue) can be used to temper symptoms. Surgery is the only curative option.
References
- ^ Verner, J. V., and Morrison, A. B. Islet cell tumor and a syndrome of refractory watery diarrhea and hypokalemia. Am J Med 1958; 374: 1958.
- ^ "Dorlands Medical Dictionary:VIPoma".
- ^ Mansour JC, Chen H. Pancreatic endocrine tumors. J Surg Res 2004; 120: 139-61. PMID 15172200
^The MERCK MANUAL Of Diagnosis And Therapy
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