Goiter ovarii
| Classification according to ICD-O-3 | |
|---|---|
| 9090/0 | Goiter ovarii |
| 9090/3 | Malignant goiter ovarii |
| ICD-O-3 first revision online | |
The goiter ovarii (lat. Goiter , glandular swelling of the neck ',' tumor ') is a predominantly unilateral, usually benign tumor of the ovaries . It is a variant of the mature teratoma , more than 50 percent of which consists of mature, regularly structured thyroid tissue . It makes up about 1 percent of all ovarian tumors and 2.7 percent of all mature teratomas. Since the ovarial goiter consists predominantly of a differentiated tissue type, the tumor is classified as one of the so-called monodermal teratomas .
history
The first description of goiter ovarii was made in 1889 by Boettlin , who had observed the presence of thyroid follicles in ovaries. Further reports were subsequently published by Gottschalk .
Epidemiology
The mean age of onset is around 45 years.
clinic
Clinically, goiter ovarii may remain symptom-free or may attract attention with pelvic pain, a palpable pelvic tumor, or abnormal vaginal bleeding. Signs of an overactive thyroid gland ( hyperthyroidism ) are also possible . In addition, accumulations of fluid in the abdominal cavity ( ascites ) and chest cavity ( pleural effusion ) are observed.
pathology
Macroscopically , there is a nodular, solid, partially cystic tumor with a shiny, yellow-brown incision. Tissue is mature thyroid tissue with normal or atrophic follicles , which are mostly lined with flattened thyrocytes and filled with colloid . Thyroid tissue can be found in 5–15% of mature teratomas, but must make up at least 50% of the tumor to justify the diagnosis of goiter ovarian. There are often adenoma-like proliferating and papillary tissue areas that have to be differentiated from a papillary thyroid carcinoma . The surrounding connective tissue shows cicatricial sclerosis and can contain lymph follicles and inflammatory cells.
Differential diagnosis
Differential diagnoses are the clear cell sarcoma , Sertoli-Leydig Cell Tumor , the endometrioid carcinoma , granulosa and by the thyroid outgoing malignancies .
forecast
As a benign neoplasm , the ovarian goiter has a good prognosis. In 2 percent of cases, however, papillary thyroid carcinomas develop and degenerate .
Individual evidence
- ↑ a b c d e W. Remmele: Pathology. Volume 4. 2nd edition. Springer, 1997, ISBN 3-540-61097-9 .
- ^ Pschyrembel Clinical Dictionary . Founded by Willibald Pschyrembel. Edited by the publisher's dictionary editor under the direction of Helmut Hildebrandt. 261st edition. De Gruyter, Berlin 2007, ISBN 978-3-11-018534-8 .
- ↑ a b c d S. C. Yoo, KH Chang, MO Lyu, SJ Chang, HS Ryu, HS Kim: Clinical characteristics of struma ovarii. In: J Gynecol Oncol. 2008 Jun; 19 (2), pp. 135-138. PMID 19471561 .
- ↑ R. Boettlin: About tooth development in dermoid cysts of the ovary. In: Virchows Arch Path Anat. 1889; 115, pp. 493-504.
- ↑ S. Gottschalk: A new type of a small cystic malignant ovarian tumor. In: Arch Gynäk. 1899; 59, pp. 676-698.
