Androblastoma

Microscopic image of an androblastoma. The Leydig cells have abundant eosinophilic or light pink cytoplasm, the cytoplasm of the Sertoli cells is pale or clear.

The androblastoma [etymology: Greek ἀνδρὀς = man and blastoma ] (syn. Arrhenoblastoma ; Greek ἅρρην = man ) is a very rare tumor of the gonads that can occur in both men in the testes and in women in the ovary . These are tumors that can originate from the Sertoli cells , the Leydig intermediate cells , or both. They can be highly or moderately differentiated, but also sarcoma - like dedifferentiated . Frequently up to 20% components of other (heterologous) tissues (cartilage, skeletal muscles, mucoid gastrointestinal epithelia) also occur. With a high Leydig content, a virilization with androgenic cell structure in vaginal cytology is evident due to testosterone formation in women .

Individual evidence

1. ↑ Elias Alexandrakis: Histopathology: textbook and atlas for assessment and differential diagnosis . Schattauer Verlag, 2006, ISBN 9783794524297 , p. 238.
2. ^ Theodor Hellbrügge: Pediatric diagnostics. Pediatric Therapy . tape 2 . Springer, Berlin 1966, ISBN 978-3-642-94950-0 , p. 621 .

This article is about a health issue. It is not used for self-diagnosis and does not replace a diagnosis by a doctor. Please note the information on health issues !