ABVD scheme

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The ABVD regimen is a chemotherapy regimen for Hodgkin's disease with a specific selection of cytostatic agents in four double cycles. The application is possible on an outpatient basis.

A driamycin 25 mg / m² iv Day 1 + 15
B leomycin 10 mg / m² iv Day 1 + 15
V inblastin 6 mg / m² iv Day 1 + 15
D acarbazine 375 mg / m² iv Day 1 + 15

(mg / m² = amount / body surface / day)

Since it through the use of dacarbazine excessive vomiting may occur, should always be - a - prophylactically to prevent a conditioning antiemetic from the group of 5-HT 3 receptor blockers ( Setrone be given).

literature

  • G. Bonadonna, R. Zucali, S. Monfardini, M. De Lena, C. Uslenghi: Combination chemotherapy of Hodgkin's disease with adriamycin, bleomycin, vinblastine, and imidazole carboxamide versus MOPP. In: Cancer. 36 (1), Jul 1975, pp. 252-259. PMID 54209