APUD

APUD ( A mine P recursor U ptake and D ecarboxylation), the outdated name for endocrine- active cells that are outside of the endocrine organs in the epithelia are other organ systems. Their appointment was made due to their capacity to absorb amino acids and decarboxylation , the more biogenic amines such as serotonin to form. All cells of the APUD come from the neural crest . Today we know that not all endocrine-disrupting cells take up amines, so the name Diffuse Neuroendocrine System (DNES) is preferred.

The concept comes from Anthony GE Pearse (1966, named 1969).

Individual evidence

^ Pearse, AG: The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept . In: J. Histochem. Cytochem. . 17, No. 5, 1969, pp. 303-13. doi : 10.1177 / 17.5.303 . PMID 4143745 .

[pearse-1] Pearse, AG: The cytochemistry and ultrastructure of polypeptide hormone-producing cells of the APUD series and the embryologic, physiologic and pathologic implications of the concept . In: J. Histochem. Cytochem. . 17, No. 5, 1969, pp. 303-13. doi : 10.1177 / 17.5.303 . PMID 4143745 .