Abductin
| Abductin | ||
|---|---|---|
| Identifier | ||
| External IDs | ||
| Occurrence | ||
| Parent taxon | Argopecten irradians | |
Abductin occurs at the junction of the two shells of Argopecten irradians and Placopecten magellanicus .
Abductin is an elastic protein from mussels .
properties
Abductin is found in the ligaments of mussels and has an unusually high elastic compressibility compared to other proteins such as elastin , resilin , spider silk and ColP . Abductin is structurally related to elastin and resilin, with an increased occurrence of the amino acids glycine and methionine . Abductin partly consists of repeat units of ten amino acids (FGGMGGGKGG or FGGMGGGNAG).
Applications
A use of Abductin has been suggested for tissue engineering or the application of active ingredients .
Individual evidence
- ^ A b Biological Materials Of Marine Origin, Biologically-Inspired Systems (2010), by Hermann Ehrlich, Volume 1, Part 4, 319–322
- ^ S. Rauscher, R. Pomès: Structural disorder and protein elasticity. In: Advances in Experimental Medicine and Biology . Volume 725, 2012, pp. 159-183, doi : 10.1007 / 978-1-4614-0659-4_10 . PMID 22399324 .
- ↑ N. Matsushima, H. Yoshida, Y. Kumaki, M. Kamiya, T. Tanaka, Y. Izumi, RH Kretsinger: Flexible structures and ligand interactions of tandem repeats consisting of proline, glycine, asparagine, serine, and / or threonine rich oligopeptides in proteins. In: Current protein & peptide science. Volume 9, Number 6, December 2008, pp. 591-610, PMID 19075749 .
- ↑ B. Bochicchio, F. Jimenez-Oronoz, A. Pepe, M. Blanco, LB Sandberg, AM Tamburro: Synthesis of and structural studies on repeating sequences of abductin. In: Macromolecular bioscience. Volume 5, Number 6, June 2005, pp. 502-511, doi : 10.1002 / mabi.200500007 . PMID 15948227 .
- ^ RE Kelly, RV Rice: Abductin: a rubber-like protein from the internal triangular hinge ligament of Pecten . Science 1967 Jan 13; 155 (3759): 208-210, PMID 6015528 .
- ↑ RS Su, JN Renner, JC Liu: Synthesis and characterization of recombinant abductin-based proteins. In: Biomacromolecules. Volume 14, number 12, December 2013, pp. 4301-4308, doi : 10.1021 / bm401162g . PMID 24147646 .