Adactyly
| Classification according to ICD-10 | |
|---|---|
| Q71.3 | Congenital absence of the hand or one or more fingers |
| Q72.3 | Congenital lack of the foot or one or more toes |
| ICD-10 online (WHO version 2019) | |
With Adaktylie - from the Greek a- (not, un-, -los) and daktylos (finger, toe) - refers to a malformation in which any or all fingers or toes missing.
Under “ Reduction defects of the upper extremity ” adactylia are classified in the ICD-10 as “Congenital absence of the hand or one or more fingers” under Q71.3, a corresponding reduction defect on the lower extremity under Q72.3.
causes
The cause is usually unclear. So far, two families with a possible were at least autosomal - dominant inheritance for a unilateral (one-sided) Adaktylie described. If external damage is assumed to be the cause, the 6th – 7th Week of embryonic development can be seen as a critical period; Finger and toe rays are visible in the human embryo on the 38th day of development.
Based on the evaluation of the data from the US Natality database from 2001 and 2002 (a total of 6,839,854 live births), smoking during pregnancy was associated with this malformation (as with other malformations of the fingers) in a dose-dependent manner.
Other
The aglossia-adactyly syndrome is a malformation syndrome with limb malformations , craniofacial anomalies and the like. a. Disruptions.
The absence of an entire extremity is called amelia , and a developmental lack of separation of individual finger or toe structures is called syndactyly . The latter can occur in combination with adactyly.
