Allan Maxam

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Allan M. Maxam (born October 28, 1942 ) is an American molecular biologist.

Maxam received his doctorate in molecular biology from Harvard University under Walter Gilbert and was there from 1980 Assistant Professor in Biology at the Dana Farber Cancer Institute. In the late 1990s he was at the Biolinguistics Institute in Cambridge, Massachusetts .

He is known for the invention of a gene sequencing method with Walter Gilbert (1977), who received the Nobel Prize in 1980 for this and who made them pioneers in genetic engineering. It combines marking (radioactive or with dyes) of DNA strands, targeted cutting of the DNA at certain bases with special reagents and gel electrophoresis . In the later gene sequencing projects, a different method was mostly used, which was developed by Frederick Sanger in 1975 , uses enzymes and allows extensive automation.

Fonts

  • Walter Gilbert, Allan Maxam: The Nucleotide Sequence of the lac Operator . In: PNAS . tape 70 , no. December 12 , 1973, p. 3581-3584 , doi : 10.1073 / pnas.70.12.3581 .
  • AM Maxam, W. Gilbert: A new method for sequencing DNA . In: PNAS . tape 74 , no. 2 , February 1977, p. 560-564 , doi : 10.1073 / pnas.74.2.560 .
  • Allan M. Maxam, Richard Tizard, Konstantin G. Skryabin, Walter Gilbert: Promoter region for yeast 5S ribosomal RNA . In: Nature . tape 267 , no. 5612 , June 16, 1977, p. 643-645 , doi : 10.1038 / 267643a0 .

Individual evidence

  1. ↑ Pamela Kalte u. a., American Men and Women of Science, Thomson Gale 2004
personal data
SURNAME Maxam, Allan
ALTERNATIVE NAMES Maxam, Allan M.
BRIEF DESCRIPTION American molecular biologist
DATE OF BIRTH October 28, 1942